DRSC/TRiP Functional Genomics Resources

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Protein Alignment Phs and Meics

DIOPT Version :9

Sequence 1:NP_648789.3 Gene:Phs / 39697 FlyBaseID:FBgn0036522 Length:971 Species:Drosophila melanogaster
Sequence 2:NP_524062.1 Gene:Meics / 39539 FlyBaseID:FBgn0025874 Length:583 Species:Drosophila melanogaster


Alignment Length:484 Identity:135/484 - (27%)
Similarity:214/484 - (44%) Gaps:97/484 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   487 QLDKSEANAGKSK-MVDQVHQQMPVESAKDHQQMTEEP--TNSTKRKRGRKERKSPTPVLIPLGD 548
            |||||.:|..:|. ....::..:|.|...     .|:|  ||.||....|.:.|  |.:..|...
  Fly    97 QLDKSNSNLSRSHCRRGTMNPLIPFEIVG-----CEDPLDTNVTKLDANRPDVK--TDIDEPTDG 154

  Fly   549 KEI---KEEP--ELPERRMR--KSRQHVDYVVEIKD--EEEDDDEVEEAEVDDDSSATISPHNSS 604
            |..   :.||  |:.|..|.  |:...|......:|  :||:|:...::|.:|....|:   .|:
  Fly   155 KATNGQESEPLQEVFEITMNDIKTEDEVSIQETFEDAFDEENDNNNTDSEREDSDQWTV---GST 216

  Fly   605 TDE----------------------------SFTSIKRESSEESQHNGIGGI---HTCNFCGKTF 638
            .|:                            |:::.|..:...::|...|..   |.|:|||:.|
  Fly   217 EDQDEPWIPGGGGRQTVGGNNQSLLCTECGVSYSTQKALARHVAKHKEQGDTQKPHLCDFCGRGF 281

  Fly   639 KRFSRMQDHLRLHTGEKPY----------------------------VCGQCGRAFRLKMRLVEH 675
            :..:::..|.|.||||:|:                            .|.||.:.|..:..|..|
  Fly   282 RTNAQLTTHRRRHTGERPFKCPLCPKAYTHGPTLKSHMHTHDEEKGHKCPQCDKTFYTRGNLRAH 346

  Fly   676 QLRHRAEKAYKCDICSMPLATKQDLSLHMRHHKNDRRYKCDKCNKGFVRSSDLSIHVRIHTGEKP 740
            ..||..|:.|||..|....|....|.||.|.||.:|.:||:.|.||||::..|..|:|:|.|::.
  Fly   347 IQRHTGERPYKCPDCPQTFAKNSGLKLHSRLHKEERPFKCELCGKGFVQNQHLITHLRVHNGDRQ 411

  Fly   741 YSCDLCGKAFRARQNLVVHRRTHLGDKPIQCELCDKRFARKIDMRVHMRRHTGEKPYNCDACQRG 805
            :.|..|.|:|..:.|::.|:|||.|.||.:||.|.:.|:....::.|:|.|||||||.||.|.:|
  Fly   412 FKCPDCDKSFFEKSNMMKHQRTHSGIKPFKCEECGQAFSHNHHLKSHLRIHTGEKPYKCDQCGKG 476

  Fly   806 YSSRVNLLRH-----QEREHGIE-EQVP---GSGQADKKHTKTATENEQENEPKA-KAAPRRPRR 860
            :|:..:|::|     ...:...: .|.|   .:.|:.:.|.||   ::..:|||. ...|....|
  Fly   477 FSANQSLMKHTLWHVDNNDRPFKCSQCPKAYDTQQSLRGHEKT---HKNPDEPKTLHQCPHCDVR 538

  Fly   861 EKLQQKIAAQEKLLNDLKRSLSAMPEIPE 889
            ..|::.:   :|.:...|......|:.||
  Fly   539 FALKKTL---DKHITSHKIRPHPCPQCPE 564

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PhsNP_648789.3 COG5048 <594..787 CDD:227381 69/251 (27%)
C2H2 Zn finger 631..651 CDD:275368 7/19 (37%)
zf-H2C2_2 644..666 CDD:290200 10/49 (20%)
zf-H2C2_2 699..724 CDD:290200 13/24 (54%)
zf-C2H2 713..735 CDD:278523 10/21 (48%)
C2H2 Zn finger 715..735 CDD:275368 9/19 (47%)
zf-H2C2_2 727..750 CDD:290200 8/22 (36%)
C2H2 Zn finger 743..763 CDD:275368 7/19 (37%)
zf-H2C2_2 755..780 CDD:290200 12/24 (50%)
C2H2 Zn finger 771..791 CDD:275368 6/19 (32%)
zf-H2C2_2 783..808 CDD:290200 13/24 (54%)
C2H2 Zn finger 799..816 CDD:275370 7/21 (33%)
MeicsNP_524062.1 zf-AD 21..95 CDD:285071
C2H2 Zn finger 242..262 CDD:275368 2/19 (11%)
C2H2 Zn finger 274..294 CDD:275368 7/19 (37%)
zf-H2C2_2 287..311 CDD:290200 7/23 (30%)
C2H2 Zn finger 302..322 CDD:275368 0/19 (0%)
C2H2 Zn finger 330..350 CDD:275368 6/19 (32%)
zf-H2C2_2 342..366 CDD:290200 9/23 (39%)
C2H2 Zn finger 358..378 CDD:275368 7/19 (37%)
C2H2 Zn finger 386..406 CDD:275368 9/19 (47%)
COG5048 <395..583 CDD:227381 54/176 (31%)
zf-C2H2 412..434 CDD:278523 7/21 (33%)
C2H2 Zn finger 414..434 CDD:275368 7/19 (37%)
zf-H2C2_2 426..451 CDD:290200 12/24 (50%)
C2H2 Zn finger 442..462 CDD:275368 6/19 (32%)
zf-H2C2_2 454..478 CDD:290200 13/23 (57%)
C2H2 Zn finger 470..486 CDD:275368 6/15 (40%)
C2H2 Zn finger 500..520 CDD:275368 6/22 (27%)
C2H2 Zn finger 532..552 CDD:275370 4/22 (18%)
C2H2 Zn finger 559..579 CDD:275370 3/6 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24377
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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