Protein Alignment Phs and CTCF

DIOPT Version :10

• Sequence 1: NP_648789.3
• Gene: Phs / 39697
• FlyBaseID: FBgn0036522
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: NP_648109.1
• Gene: CTCF / 38817
• FlyBaseID: FBgn0035769
• Length: 818
• Species: Drosophila melanogaster
• Alignment Length: 799
• Identity: 181/799 - (22%)
• Similarity: 289/799 - (36%)
• Gaps: 226/799 - (28%)

  Fly   352 MPKKRGRKRTKPESLRDEQDNAEK----TDKKKKLNKEEGQQPVLEPLQAKKTSNQAENGATQSN 412
            || :|.:|...||.|:...:|..|    ...:|.:|      .:||.:.|:
  Fly     1 MP-RRTKKDEDPEDLQTFLNNFHKEIEGNSDEKVVN------TILEAISAE-------------- 44

  Fly   413 NVVKVQQNAKGSKKDGTQSAQKSETNPKHLENAETNSKDNTESVALKETIHDKQLTIDEAGKA-- 475
             .:.:.:|  |::..|::..:::|.:..|.|.||...:|:          .||.. ||:.|..
  Fly    45 -AIDLDEN--GAEAGGSKPMEEAEADLDHAEEAEEEEEDD----------EDKYF-IDDEGNCYI 95

  Fly   476 -GTQKDDNSNQKQLDKSEANAGK---SKMVDQVHQQMPVESAKD-HQQMTEEPTNSTK------- 528
             .|.|.....||:|.::.|..||   |.:....::.:.:..||. .:..|.:|....|
  Fly    96 KTTPKKQKELQKKLKQAAAKPGKATRSVVSTATNKSINLRPAKSTPKATTSKPPPEPKAISVRPA 160

  Fly   529 RKRGRKERKS---PTPVL---IPLGDKEIKEEPELP-------ERRMRKSRQHVD---YVVEIKD 577
            |....|.::|   |.|.|   :|......::.|.:|       ||.:.:.....|   .|.|:.|
  Fly   161 RAAAAKAKQSAMPPPPALVVKVPAPRGRPRKNPVIPKPEPMDLERELEELVDEPDISSMVTELSD 225

  Fly   578 EEEDDDEVE---------EAEV--DDDSSATISPHNSSTDESFTSIKRE-----SSEESQHNGIG 626
            ...|:..||         ||||  .:|::.|...:....|..|....:|     :|..||::...
  Fly   226 YTVDEAAVEAATATLTPNEAEVYEFEDNATTEDENADKKDVDFVLSNKEVKLKTASSTSQNSNAS 290

  Fly   627 GIH------------------------------TCNFCGKTFKRFSRMQDHLRLHTGEKPYVCGQ 661
            | |                              .|:.|.::|:....:|:|:..|.|.||:.|..
  Fly   291 G-HKYSCPHCPYTASKKFLITRHSRSHDVEPSFKCSICERSFRSNVGLQNHINTHMGNKPHKCKL 354

  Fly   662 CGRAFRLKMRLVEH-QLRHRAEKAYKCDICSMPLATKQDLSLHMRHHKNDRRYKCDKCNKGFVRS 725
            |..||.....||.| :.:|..||.:||..|:........|..||..|..:|.|:|..|.......
  Fly   355 CESAFTTSGELVRHTRYKHTKEKPHKCTECTYASVELTKLRRHMTCHTGERPYQCPHCTYASQDM 419

  Fly   726 SDLSIHVRIHTGEKPYSCDLCGKAFRARQNLVVHRRTH-LGDKPI-QCELCDKRFARKIDMRVHM 788
            ..|..|:.||||||.|.||:|...|....:|..|:..| :.|||: ||..|.....||.|:|||:
  Fly   420 FKLKRHMVIHTGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCNYCPTTCGRKADLRVHI 484

  Fly   789 RR---------------------------------------------------------HTGEKP 796
            :.                                                         |..|||
  Fly   485 KHMHTSDVPMTCRRCGQQLPDRYQYKLHVKSHEGEKCYSCKLCSYASVTQRHLASHMLIHLDEKP 549

  Fly   797 YNCDACQRGYSSRVNLLRHQEREHGIEEQVPGSGQADKK---------HTKTATENEQENEPKAK 852
            ::||.|.:.:..|..|.||....|..|.|.|...:...|         |......:.:.::..|.
  Fly   550 FHCDQCPQAFRQRQLLRRHMNLVHNEEYQPPEPREKLHKCPSCPREFTHKGNLMRHMETHDDSAN 614

  Fly   853 AAPRRPRREKLQQKIAAQE-----KLLNDLKRSLSAMPEIPEES--------AQVKLDGS-GQDI 903
            |..:| ||.||.:.:..|:     .|:.|....:....|..||.        |:::.:.| .:|.
  Fly   615 AREKR-RRLKLGRNVRLQKDGTVITLIKDQYVDMDRDQEENEEDDNPESYDLAEIEPENSEAEDA 678

  Fly   904 PADAGAGHAQVQVTLSMQMEPAPNTEDDEEITPEKENALSSS----MTADGKTKANRKITSY--- 961
            ..|.   ...|...:..:::|||       |...|:..|::|    |..:.:.::.|...::
  Fly   679 DDDV---ETIVSDPIRQRIKPAP-------IIINKQARLAASEKQPMIINQRLRSQRGTKTFHIK 733

  Fly   962 -------FTV--VGQQAEI 971
                   |||  .|...|:
  Fly   734 EEPDNSDFTVEWQGDDGEV 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phs	NP_648789.3	COG5048	<594..787	CDD:227381	65/230 (28%)
		C2H2 Zn finger	631..651	CDD:275368	5/19 (26%)
		C2H2 Zn finger	715..735	CDD:275368	4/19 (21%)
		C2H2 Zn finger	743..763	CDD:275368	6/19 (32%)
		C2H2 Zn finger	771..791	CDD:275368	8/76 (11%)
		zf-H2C2_2	783..808	CDD:463886	11/81 (14%)
		C2H2 Zn finger	799..816	CDD:275370	6/16 (38%)
CTCF	NP_648109.1	FAP	116..>202	CDD:429334	17/85 (20%)
		C2H2 Zn finger	296..316	CDD:275368	0/19 (0%)
		COG5048	321..>621	CDD:227381	78/300 (26%)
		C2H2 Zn finger	324..344	CDD:275368	5/19 (26%)
		C2H2 Zn finger	352..373	CDD:275368	7/20 (35%)
		C2H2 Zn finger	381..401	CDD:275368	5/19 (26%)
		zf-H2C2_2	394..415	CDD:463886	8/20 (40%)
		C2H2 Zn finger	409..429	CDD:275368	4/19 (21%)
		zf-H2C2_2	422..446	CDD:463886	13/23 (57%)
		C2H2 Zn finger	437..457	CDD:275368	6/19 (32%)
		C2H2 Zn finger	467..485	CDD:275368	8/17 (47%)
		C2H2 Zn finger	496..516	CDD:275370	0/19 (0%)
		C2H2 Zn finger	524..544	CDD:275368	0/19 (0%)
		zf-H2C2_2	536..561	CDD:463886	7/24 (29%)
		C2H2 Zn finger	552..573	CDD:275368	7/20 (35%)
		zf-C2H2	587..609	CDD:395048	2/21 (10%)
		C2H2 Zn finger	589..609	CDD:275368	1/19 (5%)