Protein Alignment Phs and ZNF678

DIOPT Version :10

• Sequence 1: NP_648789.3
• Gene: Phs / 39697
• FlyBaseID: FBgn0036522
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: NP_848644.2
• Gene: ZNF678 / 339500
• HGNCID: 28652
• Length: 580
• Species: Homo sapiens
• Alignment Length: 98
• Identity: 26/98 - (26%)
• Similarity: 33/98 - (33%)
• Gaps: 37/98 - (37%)

  Fly   116 RKRHAEETQQP--SMPNGATTQN--------------GM-----PVPPFQPSGQDTMPPNNILFI 159
            |:.|   |..|  |.|.|.|..|              |:     ||||.:|:         |.|.
Human   386 RRAH---TPNPLHSCPCGKTFVNLTKFLYHRRTHGAGGVPLPTTPVPPEEPA---------ISFP 438

  Fly   160 HNLPIETNSMMLQLLFEQYPGFKEIRMIEAKPG 192
            ...|.||.    :|...:.|..:|.....|.||
Human   439 EPAPAETG----ELEAPELPVCEESSAEPAAPG 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phs	NP_648789.3	COG5048	<594..787	CDD:227381
		C2H2 Zn finger	631..651	CDD:275368
		C2H2 Zn finger	715..735	CDD:275368
		C2H2 Zn finger	743..763	CDD:275368
		C2H2 Zn finger	771..791	CDD:275368
		zf-H2C2_2	783..808	CDD:463886
		C2H2 Zn finger	799..816	CDD:275370
ZNF678	NP_848644.2	KRAB	43..83	CDD:460171
		COG5048	138..536	CDD:227381	26/98 (27%)
		C2H2 Zn finger	154..174	CDD:275368
		C2H2 Zn finger	182..202	CDD:275368
		C2H2 Zn finger	210..230	CDD:275368
		C2H2 Zn finger	238..258	CDD:275368
		C2H2 Zn finger	266..286	CDD:275368
		C2H2 Zn finger	294..314	CDD:275368
		C2H2 Zn finger	322..342	CDD:275368
		C2H2 Zn finger	350..370	CDD:275368
		C2H2 Zn finger	378..398	CDD:275368	5/14 (36%)
		C2H2 Zn finger	406..426	CDD:275368	1/19 (5%)
		C2H2 Zn finger	434..454	CDD:275368	6/32 (19%)
		C2H2 Zn finger	462..482	CDD:275368	3/6 (50%)
		C2H2 Zn finger	490..510	CDD:275368
		C2H2 Zn finger	518..538	CDD:275368
		zf-H2C2_2	530..555	CDD:463886