Protein Alignment Phs and Zfp711

DIOPT Version :10

• Sequence 1: NP_648789.3
• Gene: Phs / 39697
• FlyBaseID: FBgn0036522
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: NP_808415.2
• Gene: Zfp711 / 245595
• MGIID: 3045342
• Length: 805
• Species: Mus musculus
• Alignment Length: 889
• Identity: 174/889 - (19%)
• Similarity: 312/889 - (35%)
• Gaps: 255/889 - (28%)

  Fly    27 ESDMEEEEEDEEDEEEDD---------------LPDVALQID--SEDEAELE---------AQRI 65
            |:.:|.:...|||.||||               :|:.....|  |..:..||         ....
Mouse    91 EAVLEADVAIEEDLEEDDGDHILTSELITETVRVPEQVFVADLVSGPDGHLEHVVQDCVSGVDSP 155

  Fly    66 RLVEEEAAKTTKKAEKERQ----------QLQQKQQRQAQVSNGNEEQLEETQKPSNNKRKARGR 120
            .:|.||...|....|...|          .::.::.....|.:.:|:.|..:......|.:..|.
Mouse   156 TMVSEEVLVTNSDTETVIQAGGGVPGSTVTIKTEEDDDDDVKSTSEDYLMISLDDVGEKLEHMGN 220

  Fly   121 PKRKISTSSQASSASIASSATLVAAQVLADQKSRRFIYSCTSCTHHYDDNLILSRHFQLEHVEKS 185
            ...||  :|..|...:...|  ..::|:     :.:|:...:     :|::.:.   ..|.|.:|
Mouse   221 TPLKI--ASDGSQEDVKEDA--FGSEVI-----KVYIFKAEA-----EDDVEIG---GTEIVTES 268

  Fly   186 KRKRGKTKAAAEEPMVTPPLIIDPLEMGQLKPCAQLLVQGESVLQLCLACNSQFVDVVRFQEHLS 250
            :...|.:.|.          ::|           |..:|.|.::.:.:..:||..|.:...:..:
Mouse   269 EYSSGHSVAG----------VLD-----------QSRMQREKMVYMAVKDSSQEQDDISNADISN 312

  Fly   251 QQHGYFQLLVPKEEPTDLPPHAMVTIP-GALALNKANAQLQLPIPAPETPPPEQDGKEAPPSNAS 314
            :.  ..::::.:||.|.|      .|| ....:||..:    |:.:|.:....:..:......|.
Mouse   313 EL--CMEVIIGEEEGTPL------EIPLQDCDVNKTGS----PVLSPASYDERRVSRRYEECQAP 365

  Fly   315 NDKEDLTMINDMVAVIAAERVKKTSSSKVNKMIIKLPMPKKRGRKRTKPESLRDEQDNAEKTDKK 379
            .:..|..:.|....  ||:.::...|...||::      |::.:||.:.|: |..|...
Mouse   366 GNTFDSALENRNTT--AAQYLQICDSMNTNKVL------KQKIKKRRRGET-RQWQTAV------ 415

  Fly   380 KKLNKEEGQQPVLEPLQAKKTSNQAENGATQSNNVVKVQQNAKGSKKDGTQSAQKSETNPKHLEN 444
              :...:||...:.|.                 ::...:..::|..|      :..:.:|.||..
Mouse   416 --IIGPDGQPLTVYPC-----------------HICTKKFKSRGFLK------RHMKNHPDHLMR 455

  Fly   445 AETNSKDNTESVALKETIHDKQLTIDEAGKAGTQKDDNSNQKQLDKSEANAGKSKMVDQVHQQMP 509
            .:....|...:...|.:.|:..                .:.|.::|          ||:.|
Mouse   456 KKYQCTDCDFTTNKKVSFHNHL----------------ESHKLINK----------VDKTH---- 490

  Fly   510 VESAKDHQQMTEEPTNSTKRKRGRKERKSPTPVLIPLGDKEIKEEPELPERRMRKSRQHVDYVVE 574
                        |.|..|:|.|......|...:   |.|||.|         |.|.: :.||
Mouse   491 ------------EFTEYTRRYREASPLSSNKLI---LRDKEPK---------MHKCK-YCDY--- 527

  Fly   575 IKDEEEDDDEVEEAEVDDDSSATISPHNSSTDESFTSIKRESSEESQHNGIGGIHTCNFCGKTFK 639
                       |.||....:...::.|:.|..                      |.|..|||.|:
Mouse   528 -----------ETAEQGLLNRHLLAVHSKSFP----------------------HVCVECGKGFR 559

  Fly   640 RFSRMQDHLRLHTGEKPYVCGQCGRAFRL--KMRLVEH-QLRHRAEKAYKCDICSMPLATKQDLS 701
            ..|.::.|:|.|||||||.|..|  |||.  :..|..| :.:|.:...|||:.|......:::|.
Mouse   560 HPSELKKHMRTHTGEKPYQCQYC--AFRCADQSNLKTHIKSKHGSNLPYKCEHCPQAFGDERELQ 622

  Fly   702 LHMRHHKNDRRYKCDKCNKGFVRSSDLSIH-VRIHTGEKPYSCDLCGKAFRARQNLVVHRRTHLG 765
            .|:...:..:.::|..|:.....||||..| :.:||.:.|:.|::|.|.|.....|..|...|.|
Mouse   623 RHLDLFQGHKTHQCPHCDHKSTNSSDLKRHIISVHTKDFPHKCEVCDKGFHRPSELKKHSDIHKG 687

  Fly   766 -----------------------------DKPIQCELCDKRFARKIDMRVHMRRHTGEKPYNCDA 801
                                         |:.::|:.|.:.|.::.:::.||:.|||.|.|.|:.
Mouse   688 RKIHQCRHCDFKTSDPFILSGHILSVHTKDQSLKCKRCKRGFRQQNELKKHMKTHTGRKIYQCEY 752

  Fly   802 CQRGYSSRVNLLRHQEREHGIEEQVPGSGQADKKHTKTATENEQ 845
            |:...:......||....|  .:..|...:..||..:..:|.:|
Mouse   753 CEYSTTDASGFKRHVISIH--TKDYPHRCEFCKKGFRRPSEKKQ 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phs	NP_648789.3	COG5048	<594..787	CDD:227381	54/225 (24%)
		C2H2 Zn finger	631..651	CDD:275368	8/19 (42%)
		C2H2 Zn finger	715..735	CDD:275368	7/20 (35%)
		C2H2 Zn finger	743..763	CDD:275368	6/19 (32%)
		C2H2 Zn finger	771..791	CDD:275368	5/19 (26%)
		zf-H2C2_2	783..808	CDD:463886	9/24 (38%)
		C2H2 Zn finger	799..816	CDD:275370	3/16 (19%)
Zfp711	NP_808415.2	Zfx_Zfy_act	65..412	CDD:461400	68/379 (18%)
		COG5048	425..805	CDD:227381	103/488 (21%)
		C2H2 Zn finger	429..449	CDD:275368	2/42 (5%)
		C2H2 Zn finger	522..543	CDD:275368	5/35 (14%)
		C2H2 Zn finger	551..571	CDD:275368	8/19 (42%)
		C2H2 Zn finger	579..600	CDD:275368	7/22 (32%)
		C2H2 Zn finger	608..634	CDD:275368	4/25 (16%)
		C2H2 Zn finger	636..657	CDD:275368	7/20 (35%)
		C2H2 Zn finger	665..685	CDD:275368	6/19 (32%)
		C2H2 Zn finger	722..742	CDD:275368	5/19 (26%)
		C2H2 Zn finger	750..771	CDD:275368	4/20 (20%)
		C2H2 Zn finger	779..799	CDD:275368	4/16 (25%)