Protein Alignment Phs and Zic4

DIOPT Version :10

• Sequence 1: NP_648789.3
• Gene: Phs / 39697
• FlyBaseID: FBgn0036522
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: XP_011241021.1
• Gene: Zic4 / 22774
• MGIID: 107201
• Length: 403
• Species: Mus musculus
• Alignment Length: 433
• Identity: 104/433 - (24%)
• Similarity: 155/433 - (35%)
• Gaps: 130/433 - (30%)

  Fly   418 QQNAKGSKKDGTQSAQKSETNPKHLENAETNSKDNTESVALKETIHDKQLTIDEA----GKAGTQ 478
            |:.|:|.      :|:.|...|.|...|:|.......|:.:::.:...:.|:.|:    |..|.|
Mouse    32 QRRARGG------AARCSLARPPHQSQAQTQKMKYKTSLVMRKRLRLYRNTLKESSSSCGHHGPQ 90

  Fly   479 KDDNSNQKQLDKSEANAGKSKMVDQVHQQMPVESAKDHQQMTEEPTNSTKRKRGRKERKSPTPVL 543
            ...:||             ..::..:|:|.|       |.....|.|...|            :.
Mouse    91 LAASSN-------------PSVLPGLHEQPP-------QASHSRPLNGLLR------------LG 123

  Fly   544 IPLGDKEIKEEPELPERRMRKSRQHVDYVVEIKDEEEDDDEVEEAEVDDDSSATISPHNSSTDES 608
            || ||...:.||..|....|                            .|:.||.
Mouse   124 IP-GDMYARSEPFAPGPMAR----------------------------SDTLATA---------- 149

  Fly   609 FTSIKRESSEESQHNGIGGIH-TCNFCGK----TFKRFSRM---QDHLRLHTG-EKPYVCGQCGR 664
             |::          :|.||:: |.|....    .|.|:.|.   |:.:....| :.|.....|.:
Mouse   150 -TAL----------HGYGGMNLTMNLTAPHGPGAFFRYMRQPIKQELICKWLGDDSPMSPRPCSK 203

  Fly   665 AFRLKMRLVEH-QLRHRAEKAYKCDICSMPLATKQDLSLHMRHHKNDRRYKCDKCNKGFVRSSDL 728
            .|.....||.| .:.|.........||...                    :|.:..|.|.....|
Mouse   204 TFSTMHELVTHVTVEHVGGPEQANHICFWE--------------------ECPRQGKPFKAKYKL 248

  Fly   729 SIHVRIHTGEKPYSCDL--CGKAFRARQNLVVHRRTHLGDKPIQCEL--CDKRFARKIDMRVHMR 789
            ..|:|:||||||:.|..  |||.|...:||.:|:|||.|:||.:||.  |::|||...|.:.|..
Mouse   249 VNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKHSH 313

  Fly   790 RHTGEKPYNCD--ACQRGYSSRVNLLRHQEREHGIEEQVPGSG 830
            .||.:|||.|.  .|.:.|:...:|.:|. :.|| ....|.||
Mouse   314 VHTSDKPYMCKVRGCDKCYTHPSSLRKHM-KVHG-RSPPPSSG 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phs	NP_648789.3	COG5048	<594..787	CDD:227381	55/206 (27%)
		C2H2 Zn finger	631..651	CDD:275368	5/26 (19%)
		C2H2 Zn finger	715..735	CDD:275368	6/19 (32%)
		C2H2 Zn finger	743..763	CDD:275368	9/21 (43%)
		C2H2 Zn finger	771..791	CDD:275368	8/21 (38%)
		zf-H2C2_2	783..808	CDD:463886	10/26 (38%)
		C2H2 Zn finger	799..816	CDD:275370	4/18 (22%)
Zic4	XP_011241021.1	zf_ZIC	179..223	CDD:436441	9/43 (21%)
		COG5048	<200..345	CDD:227381	52/165 (32%)
		C2H2 Zn finger	235..255	CDD:275368	6/19 (32%)
		C2H2 Zn finger	263..285	CDD:275368	9/21 (43%)
		C2H2 Zn finger	293..315	CDD:275368	8/21 (38%)
		C2H2 Zn finger	323..345	CDD:275368	5/22 (23%)