Protein Alignment Phs and Zic2

DIOPT Version :10

• Sequence 1: NP_648789.3
• Gene: Phs / 39697
• FlyBaseID: FBgn0036522
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: NP_033600.3
• Gene: Zic2 / 22772
• MGIID: 106679
• Length: 529
• Species: Mus musculus
• Alignment Length: 385
• Identity: 95/385 - (24%)
• Similarity: 141/385 - (36%)
• Gaps: 78/385 - (20%)

  Fly   555 PELPERRMRKSRQHV-------DYVVEIKDEEEDDDEVEEAEVDDDSSATI----SPHNSSTDES 608
            |.|||:....:.|:|       ....|:....|...:|.....|..|:|.:    .|.|.:...:
Mouse   160 PGLPEQHGPHASQNVLNGQMRLGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMN 224

  Fly   609 FTSIKRESSEESQHNGIGGIHTCNFCGKTFKRFSRMQ-----------DHLRLHTGEKPYVCGQC 662
            ..:..........|.|            .|.|:.|.|           |..:|...:|     .|
Mouse   225 MAAAAAHHHHHHHHPG------------AFFRYMRQQCIKQELICKWIDPEQLSNPKK-----SC 272

  Fly   663 GRAFRLKMRLVEH-QLRHRAEKAYKCDICSMPLATKQDLSLHMRHHKNDRRYKCDKCNKGFVRSS 726
            .:.|.....||.| .:.|.........:|...                    :|.:..|.|....
Mouse   273 NKTFSTMHELVTHVSVEHVGGPEQSNHVCFWE--------------------ECPREGKPFKAKY 317

  Fly   727 DLSIHVRIHTGEKPYSCDL--CGKAFRARQNLVVHRRTHLGDKPIQCEL--CDKRFARKIDMRVH 787
            .|..|:|:||||||:.|..  |||.|...:||.:|:|||.|:||.|||.  ||:|||...|.:.|
Mouse   318 KLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKH 382

  Fly   788 MRRHTGEKPYNCDACQRGYSSRVNLLRHQEREHGIEEQVPGSGQADKKHTKTATENEQENEPKAK 852
            |..||.:|||.|..|.:.|:...:|.:|.:    :.|..|...::    :..|:...:.:.|...
Mouse   383 MHVHTSDKPYLCKMCDKSYTHPSSLRKHMK----VHESSPQGSES----SPAASSGYESSTPPGL 439

  Fly   853 AAP-RRPR-REKLQQKIAAQEKLLNDLKRSLSAMPEIPEESAQVKLDGSGQDIPADAGAG 910
            .:| ..|: ...|....||..........::||:    ...|.....|||....|.:|.|
Mouse   440 VSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAV----HRGAGSGSSGSGGGSAAGSGGG 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phs	NP_648789.3	COG5048	<594..787	CDD:227381	55/212 (26%)
		C2H2 Zn finger	631..651	CDD:275368	5/30 (17%)
		C2H2 Zn finger	715..735	CDD:275368	6/19 (32%)
		C2H2 Zn finger	743..763	CDD:275368	9/21 (43%)
		C2H2 Zn finger	771..791	CDD:275368	10/21 (48%)
		zf-H2C2_2	783..808	CDD:463886	11/24 (46%)
		C2H2 Zn finger	799..816	CDD:275370	4/16 (25%)
Zic2	NP_033600.3	zf_ZIC	249..294	CDD:436441	10/49 (20%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		SFP1	<328..412	CDD:227516	39/83 (47%)
		C2H2 Zn finger	334..356	CDD:275368	9/21 (43%)
		C2H2 Zn finger	364..386	CDD:275368	10/21 (48%)
		C2H2 Zn finger	394..414	CDD:275368	5/23 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	405..451		8/53 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	475..529		7/21 (33%)