Protein Alignment Phs and Zfp90

DIOPT Version :10

• Sequence 1: NP_648789.3
• Gene: Phs / 39697
• FlyBaseID: FBgn0036522
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: NP_001355257.1
• Gene: Zfp90 / 22751
• MGIID: 104786
• Length: 656
• Species: Mus musculus
• Alignment Length: 619
• Identity: 147/619 - (23%)
• Similarity: 232/619 - (37%)
• Gaps: 184/619 - (29%)

  Fly   360 RTKPESLRDEQDNAEKTDKKKKL----------------NKEEGQQPVLEPLQAKKTSNQAENGA 408
            :|:|||.|..|....:...:..:                ::|.|::.:.....::|.....|.
Mouse   108 KTRPESSRSPQQGVSEVFLRTNVLSHTTIGDIWNVAIQGHQESGRRHLGPEASSQKKITTLEK-- 170

  Fly   409 TQSNNVVKVQQNAKGSKKDGTQSAQ-------KSETNPKHLENAETNSKDNTESVALKETIHDKQ 466
                   |::||..|  :|.:.|..       .|...|...:....|.:.|:|.|.....:..|:
Mouse   171 -------KIEQNKVG--EDSSLSTDLVPQLDISSSIRPSDCKTFGNNLEHNSELVTQSNILAKKK 226

  Fly   467 LTIDEAGKAGTQKDDNSNQKQLDKSEANAGKSKMVDQVHQQMP--------VESAKDHQQMTE-- 521
                      ..|.|...:..:.:|..|..     :::|:..|        .:|.:.|.:..:
Mouse   227 ----------PYKCDKCRKSFIHRSSLNKH-----EKIHKGDPYSNGTDQGAQSGRKHHECADCG 276

  Fly   522 ----EPTNSTKRKRGRKERKSPTPVLIPLGDKEIKEEPELPERRMRKSR---QHVDYVVEIKDEE 579
                ..|..|:.:|            |..|:|..  |..:..:..|.|.   ||
Mouse   277 KTFLWRTQLTEHQR------------IHTGEKPF--ECNVCGKAFRHSSSLGQH----------- 316

  Fly   580 EDDDEVEEAEVDDDSSATISPHNSS-TDESFTSIKRESSEESQHNGIGGIHT------CNFCGKT 637
                  |.|...:      .|:..| ..::|    :.||...||.   .|||      ||.||::
Mouse   317 ------ENAHTGE------KPYQCSLCGKAF----QRSSSLVQHQ---RIHTGEKPYRCNLCGRS 362

  Fly   638 FKRFSRMQDHLRLHTGEKPYVCGQCGRAFRLKMRLVEHQLRHRAEKAYKCDICSMPLATKQDLSL 702
            |:..:.:..|...|:||||:.|.:||:||.....||:|:..|..||.::|.||.........|..
Mouse   363 FRHSTSLTQHEVTHSGEKPFQCKECGKAFSRCSSLVQHERTHTGEKPFECSICGRAFGQSPSLYK 427

  Fly   703 HMRHHKNDRRYK----------------------------CDKCNKGFVRSSDLSIHVRIHTG-- 737
            |||.||..:.|:                            |:.|.|.|...:|.|.|.|:|.|
Mouse   428 HMRIHKRSKPYQSNNFSLAFVPNTPLPQGEGLLTEVKSYHCNDCGKDFGHITDFSEHQRLHAGEN 492

  Fly   738 ------------------EKPYSCDLCGKAFRARQNLVVHRRTHLGDKPIQCELCDKRFARKIDM 784
                              ||||.|::|||||:...:.:.|.|.|.|:||.:|..|.:.|:|...:
Mouse   493 SYGSEQTLLGQQSLSHPREKPYQCNVCGKAFKRSTSFIEHHRIHTGEKPYECNECGEAFSRLSSL 557

  Fly   785 RVHMRRHTGEKPYNCDACQRGYSSRVNLLRHQEREHGIEE--QVPGSGQADKK------HTKTAT 841
            ..|.|.|||||||.|..|.:.:|...:|::| ||.|..|:  :....|:|.:|      |.:|.|
Mouse   558 TQHERTHTGEKPYECIDCGKAFSQSSSLIQH-ERTHTGEKPYECNECGRAFRKKTNLHDHQRTHT 621

  Fly   842 ENEQ-------ENEPKAKAAPRRPR---REKLQQ 865
            ..:.       .|..::.|..:..|   |.|||:
Mouse   622 GEKPYACKECGRNFSRSSALTKHHRVHARNKLQE 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phs	NP_648789.3	COG5048	<594..787	CDD:227381	72/247 (29%)
		C2H2 Zn finger	631..651	CDD:275368	6/19 (32%)
		C2H2 Zn finger	715..735	CDD:275368	8/19 (42%)
		C2H2 Zn finger	743..763	CDD:275368	8/19 (42%)
		C2H2 Zn finger	771..791	CDD:275368	6/19 (32%)
		zf-H2C2_2	783..808	CDD:463886	11/24 (46%)
		C2H2 Zn finger	799..816	CDD:275370	4/16 (25%)
Zfp90	NP_001355257.1	KRAB	34..94	CDD:214630
		COG5048	217..645	CDD:227381	120/487 (25%)
		C2H2 Zn finger	230..250	CDD:275368	3/24 (13%)
		C2H2 Zn finger	272..292	CDD:275368	3/31 (10%)
		C2H2 Zn finger	300..320	CDD:275368	5/36 (14%)
		C2H2 Zn finger	328..348	CDD:275368	6/26 (23%)
		C2H2 Zn finger	356..376	CDD:275368	6/19 (32%)
		C2H2 Zn finger	384..404	CDD:275368	8/19 (42%)
		C2H2 Zn finger	412..432	CDD:275368	7/19 (37%)
		C2H2 Zn finger	468..488	CDD:275368	8/19 (42%)
		C2H2 Zn finger	516..536	CDD:275368	8/19 (42%)
		C2H2 Zn finger	544..564	CDD:275368	6/19 (32%)
		C2H2 Zn finger	572..592	CDD:275368	7/20 (35%)
		C2H2 Zn finger	600..620	CDD:275368	4/19 (21%)
		C2H2 Zn finger	628..648	CDD:275368	3/19 (16%)