Protein Alignment Phs and Zfp61

DIOPT Version :10

• Sequence 1: NP_648789.3
• Gene: Phs / 39697
• FlyBaseID: FBgn0036522
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: NP_033587.2
• Gene: Zfp61 / 22719
• MGIID: 99663
• Length: 555
• Species: Mus musculus
• Alignment Length: 565
• Identity: 154/565 - (27%)
• Similarity: 218/565 - (38%)
• Gaps: 141/565 - (24%)

  Fly   359 KRTKPESLRDEQDNAEKTDKKKKLNKEEGQQPVLEPLQAKKTSNQAENGATQSNNVVKVQQNAKG 423
            ||.||...|:|:....:...::   ::.|            .:.|:..||.:          .:|
Mouse    49 KRDKPYLEREEKPQMRRAAPRE---RDSG------------INGQSARGAVR----------GRG 88

  Fly   424 SKK------------DGTQSAQKSETNPKHLENA----------------ETNSKDNTESVALKE 460
            |.:            |...::|.|..|...|:..                |...|.:|.||
Mouse    89 SPEALPCWQIWQWVTDDLTTSQNSVVNTPQLQGKAPCQSRPRPSAPVSVDENYIKSHTISV---- 149

  Fly   461 TIHDKQLTIDEAGKAGTQKDDNSNQKQLDKSEANAGKSKMVDQVHQQMPVESAKDHQQMTEEPTN 525
            .||..:..:......||...:...:|               ||.||....:.| ..::....||:
Mouse   150 PIHSGRPPLPTLRAQGTSLTERQTRK---------------DQYHQGSHRDEA-GQRKRDAHPTS 198

  Fly   526 STKRKRG------RKERKSPTP------VLIPLGDKEIKEEPELPERRMRKSRQHVDYVVEIKDE 578
            ...|.|.      .|.|.||:.      .::|     ..:...:..|  :||.||.:.|.::  .
Mouse   199 WIPRPRSDHRVCKSKGRCSPSDHGRDGVEVVP-----FDQNGGIHTR--QKSSQHREAVTDL--S 254

  Fly   579 EEDDDEVEEAEVDDDSSATI-------SP--------HNSSTDES---------FTSIKRESSEE 619
            ..|..:|    :|....|..       ||        ....|.|.         .|.:|..:.|:
Mouse   255 SSDPHQV----LDSGGRACACVECGRGSPCGTDGCIHQGGRTGEERKEFGHQRVCTPVKPYTCEQ 315

  Fly   620 --------SQHNGIGGIHT------CNFCGKTFKRFSRMQDHLRLHTGEKPYVCGQCGRAFRLKM 670
                    |..|....:||      |..||..|.:.|.:|||.||||||||:.|..||::|....
Mouse   316 CGKVFTCRSALNVHVKVHTRERPYNCETCGSAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRSS 380

  Fly   671 RLVEHQLRHRAEKAYKCDICSMPLATKQDLSLHMRHHKNDRRYKCDKCNKGFVRSSDLSIHVRIH 735
            .|..||..|..||.|||..|........:|.:|.|.|..::.|||..|.|.|.|.|.|..|..||
Mouse   381 HLRSHQRVHTGEKPYKCGECGKSFICSSNLYIHQRVHTGEKPYKCVDCGKEFSRPSSLQAHQGIH 445

  Fly   736 TGEKPYSCDLCGKAFRARQNLVVHRRTHLGDKPIQCELCDKRFARKIDMRVHMRRHTGEKPYNCD 800
            ||||.|.|.:|||.:....||.||.|.|.|:||..|::|.|.|:|...::.|.|.|||||||.||
Mouse   446 TGEKSYVCTMCGKGYTLNSNLQVHLRVHTGEKPYSCDVCGKGFSRSSQLQSHQRVHTGEKPYKCD 510

  Fly   801 ACQRGYSSRVNLLRHQEREHGIEEQ-VPGSGQADKKHTKTATENE 844
            .|.:.:..|.||:.|    |.|... .|...:.|.|:.|.:|:.:
Mouse   511 VCGKSFGWRSNLIIH----HRIHSSGKPYKSKRDDKNIKESTQEK 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phs	NP_648789.3	COG5048	<594..787	CDD:227381	81/230 (35%)
		C2H2 Zn finger	631..651	CDD:275368	9/19 (47%)
		C2H2 Zn finger	715..735	CDD:275368	8/19 (42%)
		C2H2 Zn finger	743..763	CDD:275368	9/19 (47%)
		C2H2 Zn finger	771..791	CDD:275368	7/19 (37%)
		zf-H2C2_2	783..808	CDD:463886	12/24 (50%)
		C2H2 Zn finger	799..816	CDD:275370	6/16 (38%)
Zfp61	NP_033587.2	KRAB	4..63	CDD:214630	6/13 (46%)
		C2H2 Zn finger	313..333	CDD:275368	3/19 (16%)
		COG5048	<338..526	CDD:227381	85/191 (45%)
		C2H2 Zn finger	341..361	CDD:275368	9/19 (47%)
		C2H2 Zn finger	369..389	CDD:275368	7/19 (37%)
		C2H2 Zn finger	397..417	CDD:275368	5/19 (26%)
		C2H2 Zn finger	425..445	CDD:275368	8/19 (42%)
		C2H2 Zn finger	453..473	CDD:275368	9/19 (47%)
		C2H2 Zn finger	481..501	CDD:275368	7/19 (37%)
		C2H2 Zn finger	509..529	CDD:275368	8/23 (35%)