Protein Alignment CG7650 and PDCL3

DIOPT Version :10

• Sequence 1: NP_648786.1
• Gene: CG7650 / 39694
• FlyBaseID: FBgn0036519
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_076970.1
• Gene: PDCL3 / 79031
• HGNCID: 28860
• Length: 239
• Species: Homo sapiens
• Alignment Length: 213
• Identity: 61/213 - (28%)
• Similarity: 105/213 - (49%)
• Gaps: 35/213 - (16%)

  Fly    69 KGVVKDWQRFKQLEAERRDETERQRLALAKKLTITATTSAEDEERKRQEELDAELDELMSED--F 131
            ||::...:..|:||.|..:|   ||:     |..:...:.||   ...|||:...||...||  .
Human    17 KGILPPKESLKELEEEAEEE---QRI-----LQQSVVKTYED---MTLEELEDHEDEFNEEDERA 70

  Fly   132 LQQYQKQRMAEMLRQTGHHQQFGQVQQLTSHEEFLACVEQENKHTTIIIHIYERQLAACATLNKC 196
            ::.|:::|:||. :.|....:||:|.:: |.::::..|.:..:...:|:|:|::.:..||.:|:.
Human    71 IEMYRRRRLAEW-KATKLKNKFGEVLEI-SGKDYVQEVTKAGEGLWVILHLYKQGIPLCALINQH 133

  Fly   197 LDSLASDYPSIKFAKICSSVAGMSRDFRTKGLPALLVY-----KAQAVIGNFV----RLTDDLSD 252
            |..||..:|.:||.|..|:..  ..::..:.||.:.||     ||| .||..|    .||.|
Human   134 LSGLARKFPDVKFIKAISTTC--IPNYPDRNLPTIFVYLEGDIKAQ-FIGPLVFGGMNLTRD--- 192

  Fly   253 DFFASDVESFLIEHGIIV 270
                 ::|..|.|.|.|:
Human   193 -----ELEWKLSESGAIM 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7650	NP_648786.1	Phd_like_Phd	60..267	CDD:239285	59/208 (28%)
PDCL3	NP_076970.1	Phd_like_VIAF	8..202	CDD:239286	59/208 (28%)
		Thioredoxin fold. /evidence=ECO:0000250	91..239		37/127 (29%)
		Interaction with XIAP. /evidence=ECO:0000269|PubMed:19012568	97..99		0/2 (0%)
		Interaction with XIAP. /evidence=ECO:0000269|PubMed:19012568	153..155		0/3 (0%)