DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7650 and Pdcl

DIOPT Version :9

Sequence 1:	NP_648786.1	Gene:	CG7650 / 39694	FlyBaseID:	FBgn0036519	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_071583.1	Gene:	Pdcl / 64013	RGDID:	621135	Length:	301	Species:	Rattus norvegicus

Alignment Length:	290	Identity:	129/290 - (44%)
Similarity:	181/290 - (62%)	Gaps:	31/290 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MATLEDKLLGEKLEYYCSSSEGEDNGDEGGD-NKGASGKSRCSGLTIDTNPDATPAGGFRQQSST 64
            |.||:||||||||:||.|:||.||:..|..| .:||...|       .|..:|..||   :..|.
  Rat     1 MTTLDDKLLGEKLQYYYSTSEDEDSDHEDKDRGRGAPASS-------STPAEAELAG---EGISV 55

  Fly    65 NTGPKGVVKDWQRFKQLEAERRDETERQRLALAKKLTITATTSA-EDEERKRQEEL--------- 119
            |||||||:.||:||||||.|:|:|..|:...|.|||:::..:.. |:||:::|::|
  Rat    56 NTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMSCRSHLDEEEEQQKQKDLQEKISGKMT 120

  Fly   120 -------DAELDELMSEDFLQQYQKQRMAEMLRQTGHHQQFGQVQQLTSHEEFLACVEQENKHTT 177
                   |..||:   |:|||||:||||.||.:|.....||.||.::.|.|.||..:::|.|.|.
  Rat   121 LKECGMMDKNLDD---EEFLQQYRKQRMDEMRQQLHKGPQFKQVLEIPSGEGFLDMIDKEQKSTL 182

  Fly   178 IIIHIYERQLAACATLNKCLDSLASDYPSIKFAKICSSVAGMSRDFRTKGLPALLVYKAQAVIGN 242
            |::||||..:.....:|.|:..||::||::||.::.|||.|.|..|....|||||:|||..:|||
  Rat   183 IMVHIYEDGVPGTEAMNGCMICLAAEYPTVKFCRVRSSVIGASSRFTRNALPALLIYKAGELIGN 247

  Fly   243 FVRLTDDLSDDFFASDVESFLIEHGIIVDR 272
            |||:||.|.:||||.|:|:||.|.|::.::
  Rat   248 FVRVTDQLGEDFFAVDLEAFLQEFGLLPEK 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7650	NP_648786.1	Phd_like_Phd	60..267	CDD:239285	101/223 (45%)
Pdcl	NP_071583.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	15..60		20/54 (37%)
		Phosducin	35..299	CDD:251094	109/256 (43%)
		Phd_like_Phd	51..272	CDD:239285	101/223 (45%)
		Thioredoxin fold. /evidence=ECO:0000250	158..301		56/120 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352659
Domainoid	1	1.000	191	1.000	Domainoid score	I3142
eggNOG	1	0.900	-	-		E1_KOG3171
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38043
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3440
OMA	1	1.010	-	-		QHG55912
OrthoDB	1	1.010	-	-		D1324495at2759
OrthoFinder	1	1.000	-	-		FOG0002881
OrthoInspector	1	1.000	-	-		otm45977
orthoMCL	1	0.900	-	-		OOG6_105152
Panther	1	1.100	-	-	LDO	PTHR46052
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2239
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770