DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7650 and pdcl

DIOPT Version :9

Sequence 1:	NP_648786.1	Gene:	CG7650 / 39694	FlyBaseID:	FBgn0036519	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_955941.2	Gene:	pdcl / 323645	ZFINID:	ZDB-GENE-030131-2365	Length:	306	Species:	Danio rerio

Alignment Length:	286	Identity:	118/286 - (41%)
Similarity:	180/286 - (62%)	Gaps:	22/286 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MATLEDKLLGEKLEYYCSSSEGEDNGDEGGDNKGASGKSRCSGLTIDTNPDATPAGGFRQQSSTN 65
            |.||:||:|||||:||.||||.|::..|..:|   :.|:......:|...|.:..|     ||.|
Zfish     1 MTTLDDKILGEKLQYYYSSSEDEESDHEEDEN---AHKTIRDQEVLDVELDYSADG-----SSVN 57

  Fly    66 TGPKGVVKDWQRFKQLEAERRDETERQRLALAKKLTITATTSAEDE-ERKRQEELDAEL------ 123
            ||||||:.||:::||||.|:|.|.:::...|.|||::|..:..|:| ::::|:||..:|
Zfish    58 TGPKGVINDWRKYKQLENEQRIEQQKEMEKLIKKLSMTCKSHLEEEADKQKQKELQDKLTGKLNL 122

  Fly   124 --DELMSED-----FLQQYQKQRMAEMLRQTGHHQQFGQVQQLTSHEEFLACVEQENKHTTIIIH 181
              ||...||     |||||:.|||.:|.||....::|.:|..::|.||||..|::|.|.|.:::|
Zfish   123 RVDEEEEEDDDDEAFLQQYRLQRMEQMRRQLCGGRRFEKVMDISSGEEFLRAVDEEGKSTLVLVH 187

  Fly   182 IYERQLAACATLNKCLDSLASDYPSIKFAKICSSVAGMSRDFRTKGLPALLVYKAQAVIGNFVRL 246
            |||.::.||..::..|..||..||.:||.::..|..|.|..||:..|||||:|:...::||.||:
Zfish   188 IYEPEVPACQAMDGSLLCLALQYPMVKFCRVRGSAVGTSALFRSSALPALLLYRGGDLVGNLVRV 252

  Fly   247 TDDLSDDFFASDVESFLIEHGIIVDR 272
            :|.|.|||:|:|||:.|.|:|::.::
Zfish   253 SDQLGDDFYATDVEALLQEYGLLPEK 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7650	NP_648786.1	Phd_like_Phd	60..267	CDD:239285	94/220 (43%)
pdcl	NP_955941.2	Phosducin	46..295	CDD:251094	97/238 (41%)
pdcl	NP_955941.2	Phd_like_Phd	52..273	CDD:239285	95/225 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594600
Domainoid	1	1.000	182	1.000	Domainoid score	I3401
eggNOG	1	0.900	-	-		E1_KOG3171
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38043
Inparanoid	1	1.050	212	1.000	Inparanoid score	I3626
OMA	1	1.010	-	-		QHG55912
OrthoDB	1	1.010	-	-		D1324495at2759
OrthoFinder	1	1.000	-	-		FOG0002881
OrthoInspector	1	1.000	-	-		oto41751
orthoMCL	1	0.900	-	-		OOG6_105152
Panther	1	1.100	-	-	LDO	PTHR46052
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4364
SonicParanoid	1	1.000	-	-		X2239
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	16	15.840