DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7656 and UBE2I

DIOPT Version :9

Sequence 1:	NP_648783.4	Gene:	CG7656 / 39691	FlyBaseID:	FBgn0036516	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_005255597.1	Gene:	UBE2I / 7329	HGNCID:	12485	Length:	184	Species:	Homo sapiens

Alignment Length:	184	Identity:	65/184 - (35%)
Similarity:	83/184 - (45%)	Gaps:	44/184 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 SSSAVRALAMEYKSLQEEPVEGF-RVKLINDD---NLFEWEVAIFGPPDTLYQGGYFKAHMKFPH 98
            |..|:..||.|.|:.:::...|| .|...|.|   ||..||.||.|...|.::||.||..|.|..
Human     2 SGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKD 66

  Fly    99 DYPYSPPSIRFLTKVWHPNVYENGDLCISILHPPVDDPQSGELPCERWNPTQNVRTILLSVISLL 163
            |||.|||..:|...::|||||.:|.:|:|||....|           |.|...::.|||.:..||
Human    67 DYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKD-----------WRPAITIKQILLGIQELL 120

  Fly   164 NEPNTFSPANVDASVMY-----------------------RRWR------DSQG 188
            ||||...||..:|..:|                       |.||      ||||
Human   121 NEPNIQDPAQAEAYTIYWLVAALAPLVAAPPRPSQGRLAGREWRTQAHPTDSQG 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7656	NP_648783.4	UBCc	42..186	CDD:238117	59/176 (34%)
CG7656	NP_648783.4	COG5078	45..182	CDD:227410	56/163 (34%)
UBE2I	XP_005255597.1	COG5078	1..137	CDD:227410	57/145 (39%)
UBE2I	XP_005255597.1	UQ_con	8..137	CDD:278603	55/139 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910