Protein Alignment CG7656 and Cdc34

DIOPT Version :10

• Sequence 1: NP_648783.4
• Gene: CG7656 / 39691
• FlyBaseID: FBgn0036516
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_808281.1
• Gene: Cdc34 / 216150
• MGIID: 102657
• Length: 235
• Species: Mus musculus
• Alignment Length: 235
• Identity: 155/235 - (65%)
• Similarity: 189/235 - (80%)
• Gaps: 8/235 - (3%)

  Fly    37 PSSSAVRALAMEYKSLQEEPVEGFRVKLINDDNLFEWEVAIFGPPDTLYQGGYFKAHMKFPHDYP 101
            |||.  :||.:|.|.|||||||||||.|:::.:|:.|||||||||:|.|:||||||.:|||.|||
Mouse     7 PSSQ--KALLLELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYP 69

  Fly   102 YSPPSIRFLTKVWHPNVYENGDLCISILHPPVDDPQSGELPCERWNPTQNVRTILLSVISLLNEP 166
            ||||:.|||||:||||:||.||:||||||||||||||||||.|||||||||||||||||||||||
Mouse    70 YSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEP 134

  Fly   167 NTFSPANVDASVMYRRWRDSQGKDNEYPNIIRKQALAANAEAKREGIVVPMTLEDYCLKPTRKPT 231
            |||||||||||||||:|::|:|||.||.:|||||.|....:|:|:|:.||.||.:||:| |:.|.
Mouse   135 NTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVK-TKAPA 198

  Fly   232 TESGLDANFYDDDF-DLETEDDLPSDDDFDEDDDDDEDED 270
            .:.|.|. ||||.: |.|.|:   :|..|.:::||...|:
Mouse   199 PDEGSDL-FYDDYYEDGEVEE---ADSCFGDEEDDSGTEE 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7656	NP_648783.4	UBCc_UBE2R	43..212	CDD:467423	128/168 (76%)
Cdc34	NP_808281.1	UBCc_UBE2R	11..180	CDD:467423	128/168 (76%)
		Important for ubiquitin transfer. /evidence=ECO:0000250|UniProtKB:P49427	98..113		13/14 (93%)
		SCF-binding. /evidence=ECO:0000250|UniProtKB:P49427	190..235		19/50 (38%)