DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AIMP2 and aimp2

DIOPT Version :9

Sequence 1:	NP_648782.2	Gene:	AIMP2 / 39690	FlyBaseID:	FBgn0036515	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_998503.1	Gene:	aimp2 / 406647	ZFINID:	ZDB-GENE-040426-2652	Length:	321	Species:	Danio rerio

Alignment Length:	336	Identity:	81/336 - (24%)
Similarity:	129/336 - (38%)	Gaps:	93/336 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MYELKTLLP-QFDIKLPTCMYPLKNVSLAADSLASGSSTSASTSASTSSCKLEANRIDRTGRNAA 64
            ||::|.:.| ...:.||||||.|.||.      |.|        ||.....|:...:|.|
Zfish     3 MYQVKPVSPADITVDLPTCMYKLPNVH------AQG--------ASLGEHALQNGEVDPT----- 48

  Fly    65 TCALDLDSLGRQIQRLLKDDTASVAARQEKVLKQLEELKAQLGQIRAGL---------GVCGKTF 120
                                ..::..||:::|::|.||||.:..:...:         .....|.
Zfish    49 --------------------VKALEERQDEILRKLYELKATVDGLAKTVTTPDADLDASTLAHTL 93

  Fly   121 QHTTAFQ----NGGLKEV------PLQDVVINGHPNFIPYALLALKNAWRNLYTIDVKTFTHSTM 175
            .||.|..    ...|.::      .|:|:|||.:|...|.:||.|.......:.:......||::
Zfish    94 THTPADAVLRGTADLDDLLGKDLGALRDIVINANPAQPPLSLLVLHALLCQRFQVLSSVHVHSSV 158

  Fly   176 ADI--------GP------AAREFEANLAKVPVNPALPKISVTLIWKNCEHTEMISSPTMYVPIY 226
            :.:        ||      |...|:              :..|||||:....:|..|.....||.
Zfish   159 STVPAPLLSCLGPRHTHSYARHRFQ--------------LGFTLIWKDVSKLQMKFSTQNMCPIE 209

  Fly   227 GEVNIIRYLGRVGPAEYRYEGSPLCNE--IDLVLDICYQLLRCNTHKTQVAMVRLLDKRLQKQQY 289
            ||.|:.|:|.|:..||.|...|....:  :|..|   :||....: |.:.|::|.|:..|.:..:
Zfish   210 GEGNVARFLYRLLGAEPRDPVSATLMDGWVDTAL---FQLAEGGS-KERAAVLRALNAALGRSPW 270

  Fly   290 FGGSQMSVADV 300
            ..|.:.|:||:
Zfish   271 LLGQEFSLADI 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AIMP2	NP_648782.2	GST_C_family	<275..327	CDD:198286	8/26 (31%)
aimp2	NP_998503.1	AIMP2_LysRS_bd	1..31	CDD:293385	13/33 (39%)
aimp2	NP_998503.1	GST_C_AIMP2	215..310	CDD:198309	20/71 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586544
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N3G
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	64	1.000	Inparanoid score	I5373
OMA	1	1.010	-	-		QHG49981
OrthoDB	1	1.010	-	-		D1382507at2759
OrthoFinder	1	1.000	-	-		FOG0007974
OrthoInspector	1	1.000	-	-		oto39760
orthoMCL	1	0.900	-	-		OOG6_108313
Panther	1	1.100	-	-	LDO	PTHR13438
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9405
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.800