Protein Alignment CG12301 and UTP14

DIOPT Version :10

• Sequence 1: NP_648781.1
• Gene: CG12301 / 39689
• FlyBaseID: FBgn0036514
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_013617.1
• Gene: UTP14 / 854881
• SGDID: S000004558
• Length: 899
• Species: Saccharomyces cerevisiae
• Alignment Length: 799
• Identity: 198/799 - (24%)
• Similarity: 341/799 - (42%)
• Gaps: 153/799 - (19%)

  Fly     1 MSDDEEHYEPKAHKKLLQAIGSLGKVQHIQKSTRDER-----QSLQDEFQLVKGVSSAETDHAPR 60
            :|:|||..|       |..|.|  |:....||...:|     ....:|:.|   .|:.....|..
Yeast   188 ISEDEEDIE-------LNTITS--KLIDETKSKAPKRLDTYGSGEANEYVL---PSANAASGASG 240

  Fly    61 AVGLNDLVDILRTSTKHSQTGKKLKNIHGSKKVLQKPLEKPAADRIKRTIGYEGVTKKLGRWDAV 125
            .:.|.|:::::    ...|..:....:.|.....:.||.:....|..|...||...:::.:|:.:
Yeast   241 KLSLTDMMNVI----DDRQVIENANLLKGKSSTYEVPLPQRIQQRHDRKAAYEISRQEVSKWNDI 301

  Fly   126 VAQQRSAETQIFPLPSETVYVNTAANARPLN---TRVKSNLAQELEANNRKLRELRKAQIGDTTD 187
            |.|.|.|:..||||...|.:.:.:|..|..:   |.::..:.|.|:.:|.            ...
Yeast   302 VQQNRRADHLIFPLNKPTEHNHASAFTRTQDVPQTELQEKVDQVLQESNL------------ANP 354

  Fly   188 EKELAKQERLLLQKKLTRDELFARRKELAYLKMRESQKSAKARMQNKIKSKKFHKLQKRQKMLEQ 252
            ||:...:|  |...|:|.:|:..|..|:..::....::..|||...|||||.:.|::|:    |.
Yeast   355 EKDSKFEE--LSTAKMTPEEMRKRTTEMRLMRELMFREERKARRLKKIKSKTYRKIKKK----EL 413

  Fly   253 MKEFELLQKTDPEAALEKLNALEKSRVQERASLRHKNTGTWAKNLQIRAKY----DKDVRKDLAE 313
            ||..||...:..|...:.    :.:|.:||.:|:||....|||::   .|:    |.:.|:::.|
Yeast   414 MKNRELAAVSSDEDNEDH----DIARAKERMTLKHKTNSKWAKDM---IKHGMTNDAETREEMEE 471

  Fly   314 QLAVSRELTQKKQVSDSEDE-----TTKKRVLPEEEDN-DYDPF-NPWTKRKATEQTENGNGESE 371
            .|.....|..|....:|:||     .|...|..||::| |.:.. :...|..........|||:.
Yeast   472 MLRQGERLKAKMLDRNSDDEEDGRVQTLSDVENEEKENIDSEALKSKLGKTGVMNMAFMKNGEAR 536

  Fly   372 GSNWRQYWTKRNKNEKLLEEHRRDLEGVQDND-----EQEEKETIRKPLIEVKPAKKKLKKSKVK 431
                     :|..|::.|    |.|..|::.|     |.:|:||               ....::
Yeast   537 ---------EREANKETL----RQLRAVENGDDIKLFESDEEET---------------NGENIQ 573

  Fly   432 IENGWEVEDICPTDQKEAKASPNSKAIDDIFEKHEDHIRAKLNKKMEKLRERINKLKEVPVKGKK 496
            |..|..:            .:|.|...:....:..||.|.:  .|:::.|...|:|        :
Yeast   574 INKGRRI------------YTPGSLESNKDMNELNDHTRKE--NKVDESRSLENRL--------R 616

  Fly   497 AKKKDVLQNLKSLALKKTKQQIEID-EPL----NYEEDKNSQNNIP----AHVEGNTESTEIPAV 552
            ||.....:|.::.|......:.|.| |||    |.::|:.:::..|    ...|.:|...:...|
Yeast   617 AKNSGQSKNARTNAEGAIIVEEESDGEPLQDGQNNQQDEEAKDVNPWLANESDEEHTVKKQSSKV 681

  Fly   553 DTIDP---------NKVTTLVFTQKKGNSGGFND--------------ALIDDEAAEYDEEDAAA 594
            :.||.         ||:......|||...|..||              .::|......||:....
Yeast   682 NVIDKDSSKNVKAMNKMEKAELKQKKKKKGKSNDDEDLLLTADDSTRLKIVDPYGGSDDEQGDNV 746

  Fly   595 ---ERQLTISQAFEDDDIVADFNRDKSK--DSELKNTELQLALPGWGSWAGAGISKEVMERRNKR 654
               ::|..|::||..||:||:|..:|.:  |.| .:.|:...|||||.|||||...:..:|:..:
Yeast   747 FMFKQQDVIAEAFAGDDVVAEFQEEKKRVIDDE-DDKEVDTTLPGWGEWAGAGSKPKNKKRKFIK 810

  Fly   655 LLLKLAAPEKRRDENKDNLYLNESASKQARQHMVSSIPFPFRSLADYEASIRAPVGRNFVPETAF 719
            .:..:...:||||:|..|:.:||..:|:..::..|::||||.:...||.|:|.|:|:.:....:.
Yeast   811 KVKGVVNKDKRRDKNLQNVIINEKVNKKNLKYQSSAVPFPFENREQYERSLRMPIGQEWTSRASH 875

  Fly   720 RMLTRPAVITRKGQVIEPM 738
            :.|.:|.::|:.||||:|:
Yeast   876 QELIKPRIMTKPGQVIDPL 894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12301	NP_648781.1	Utp14	15..738	CDD:461368	192/783 (25%)
UTP14	NP_013617.1	COG5644	1..898	CDD:227931	198/799 (25%)