Protein Alignment CG12301 and Utp14a

DIOPT Version :10

• Sequence 1: NP_648781.1
• Gene: CG12301 / 39689
• FlyBaseID: FBgn0036514
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_001014135.2
• Gene: Utp14a / 317579
• RGDID: 1359313
• Length: 765
• Species: Rattus norvegicus
• Alignment Length: 807
• Identity: 231/807 - (28%)
• Similarity: 390/807 - (48%)
• Gaps: 119/807 - (14%)

  Fly     1 MSDDEEHY---EPKAHKKLLQAIGSLGKVQHIQKSTRDERQSLQDEFQLVKGVSSAETDHAPRAV 62
            :||.|:..   ..:.|:|||:|||||......:...|.|......||    .|||   :.:...:
  Rat    28 LSDSEDEAGSDGERKHQKLLEAIGSLSGKNRWKLPERSEAGLKVSEF----NVSS---EGSGEKL 85

  Fly    63 GLNDLVDILRTSTKHSQTGKKLKNIHGSKKVLQKPLEKPAADRIKRTIGYEGVTKKLGRWDAVVA 127
            .|:||::.|::|:..:...|:|..:. |||.|:.||.|...:|:.|.:.:...::.|.:||:||.
  Rat    86 ALSDLLEPLKSSSSLAAVKKQLNRVK-SKKTLELPLHKGEVERVHREVAFSNTSQALSKWDSVVQ 149

  Fly   128 QQRSAETQIFPLPSETVYVNTAANARPL-----NTRVKSNLAQELEANNRKLRELRKAQIGDTTD 187
            :.|:||..:|||..|..:|       |:     ..:.:|.|.||:    ..|....|..:.|..
  Rat   150 KNRAAEQLVFPLEKEPTFV-------PMEHVFCEWKARSPLEQEI----FNLLHKNKQPVTDPL- 202

  Fly   188 EKELAKQERLLLQKKLTRDELFARRKELAYLKMRESQKSAKARMQNKIKSKKFHKLQKRQKMLEQ 252
               |...|:..| |.::.:|...||.||...:..:|...|:||...||||||:||:.|:.|..:.
  Rat   203 ---LTPVEKASL-KAMSLEEAKIRRAELQRARALQSYYEARARRMKKIKSKKYHKIVKKGKAQKA 263

  Fly   253 MKEFELLQKTDPEAALEKLNALEKSRVQERASLRHKNTGTWAKNLQIRAKYDKDVRKDLAEQLAV 317
            :|:||.|:|.||:||||:|..:||:|:.||.||:|:|:|.|||:..|.||||.:.|:.:.||||.
  Rat   264 LKDFEQLRKVDPDAALEELEKMEKARMLERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLAK 328

  Fly   318 SRELTQKKQ-VSDSEDETTKKR-------VLPEEEDNDYDPFNPWTKRKATEQTENGNGESEGSN 374
            ::|||||.| ||:||:|...:.       ::.|.:...:.| |||..|......:....:::...
  Rat   329 NKELTQKLQVVSESEEERDAEEEEALVPDIVNEVQKAAHGP-NPWMLRSCNHDAKENEIQADPEQ 392

  Fly   375 WRQ----YWTKRNKNEKLLEEHRRDLEGVQDNDEQEEKETIRKPLIEVKPAKKKLKKSKVKIENG 435
            ..:    .::|...:||.:.|..:.||      |.|::.::|             |:|::.
  Rat   393 LPEPAAPEFSKNEGDEKPVAEEGKLLE------ELEKRRSLR-------------KRSELN---- 434

  Fly   436 WEVEDICPTDQKEAKASPNSKAIDDIFEKHEDHIRAKLNKKMEKLRERINKLKEVPVK--GKKAK 498
               .|..|...::.|.|.|.:.:.:        :|| |:||:.|......|.||.|.|  |...:
  Rat   435 ---HDAEPARDQKPKDSTNQEVLSE--------LRA-LSKKLSKENHPFEKQKESPAKTVGLVQE 487

  Fly   499 KKDVLQNLKSLALKKTKQQIEIDEPLNYEEDKNSQNNIP------AHVEGNTESTEIPAVDTIDP 557
            ::...:..:.|.|::.::...::|    .|:...:.::|      ..|||....|. |...|...
  Rat   488 EEPGPEEDEPLLLQRPERVRTLEE----LEELGKEYSLPNKELSRPSVEGEQMRTN-PQNQTKGK 547

  Fly   558 NKVTTLVFTQK--KGNSGGFNDALIDDEAAEYDEEDAAAERQLTISQAFEDDDIVADFNRDKSKD 620
            ||...::..|.  ...:.......:.....|.|:|....::|: |.:||..||::.:|.::|.:.
  Rat   548 NKKEQMISLQNLLTTRTPSVTSLALPTTVEELDDEVKRNQKQM-IKEAFAGDDVIKEFLKEKREA 611

  Fly   621 SEL-KNTELQLALPGWGSWAGAGISKEVMERRNKRLLLKLAAPE--KRRDENKDNLYLNESASKQ 682
            .:. |..::.|.|||||.|.|..:.....:||  |.|:|  |||  .|:|:|..|:.:||..:..
  Rat   612 VQANKPKDVDLTLPGWGEWGGMDLKPSAKKRR--RFLIK--APEGPPRKDKNLPNVIINEKRNIH 672

  Fly   683 ARQHMVSSIPFPFRSLADYEASIRAPVGRNFVPETAFRMLTRPAVITRKGQVIEPMTESEL---- 743
            ...|.|..:|:||.....:|.:|:.|:|..::.:.||:.||.|.|:|:.|.:|:|:|..::
  Rat   673 IAAHQVRVLPYPFTHHQQFERTIQNPIGSTWITQRAFQKLTAPKVVTKPGHIIKPITADDVGRQS 737

  Fly   744 ----------VKPDRRLRHIVDRRIKR 760
                      ..|.|..:|  .:::|:
  Rat   738 SPRSDLSVMQTNPKRHCKH--QKQLKK 762

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12301	NP_648781.1	Utp14	15..738	CDD:461368	221/752 (29%)
Utp14a	NP_001014135.2	Utp14	44..730	CDD:461368	222/755 (29%)