Protein Alignment mrn and TFB2

DIOPT Version :10

• Sequence 1: NP_648780.1
• Gene: mrn / 39688
• FlyBaseID: FBgn0261109
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_015203.1
• Gene: TFB2 / 855981
• SGDID: S000006043
• Length: 513
• Species: Saccharomyces cerevisiae
• Alignment Length: 513
• Identity: 175/513 - (34%)
• Similarity: 274/513 - (53%)
• Gaps: 71/513 - (13%)

  Fly    39 EYLRTRQTPESLE-KLYNYPPICLAVFRELPEIARQFIIRILFVDQPVPQAVVTSWGAQRCAKEQ 102
            :||  .:.|:.:: :||..|..|||::|.||.:|:.||:.::|.:..||...:..|.......:.
Yeast    12 QYL--EEIPQQVQNRLYTSPATCLAIYRILPPLAKFFIMAMVFNENEVPLLDLDKWVNSNGKLQF 74

  Fly   103 AEATSCLTALNVWRVTAIP---GGLSAWELSPTFKKSVRQVLLGGGKPWPMTNTLDKDSKPRDIA 164
            ..|...:.:|::    .||   .|.....|:||||.|:|..|.||.........::::....|:
Yeast    75 QNAIKSMKSLHL----LIPNKSSGTLMINLNPTFKISLRNALTGGEVQNSFGVVVEENVVSLDL- 134

  Fly   165 FLDTYAMSRWRCVLHYMVGTGNRNGTDAEAISPDAVRILLHANLMKRDERDG-ITITRQGFQFLL 228
             ||.|:.::|..:||:||||     ..|:..|...:.:|.|:.||:.....| ..||.:||||||
Yeast   135 -LDEYSANKWETILHFMVGT-----PLAKIPSEKVLNLLKHSKLMEEVNSTGEFKITNEGFQFLL 193

  Fly   229 LDTRAQVWHFMLQYLDTCEERGISLPECLSMLFQLSFSTLGRDYSSEGMNSQMLTFLQHLREFGL 293
            .:..:|:|..:||||...|...:.|.:.|..:|.|....:|:.|..:.::......||.:|::||
Yeast   194 QEINSQLWTLLLQYLKMIETSKMDLVDVLHFIFMLGALEVGKAYKIDALSETQRIMLQDMRDYGL 258

  Fly   294 VFQRKRKEGRFYPTRLALNVTS-KEAAATASVAMDE------------------EATQDC----- 334
            |||:...:..||||:|||.:|| .:...:||.|||.                  ::|.|.
Yeast   259 VFQKHSNDSIFYPTKLALMLTSDTKTIRSASNAMDSVLRQNREEPSVNEDGANGKSTTDITTSDD 323

  Fly   335 -------------GYIVVETNYRVYAYTDSPLQVAVLGLFTELLYRFPNLVVGVLTRDSVRQALR 386
                         |.::||||:::|:|::||||:|||.||..|..||.|:|:|.:||:|:|:||.
Yeast   324 LNKAGLKNQDIPDGSLIVETNFKIYSYSNSPLQIAVLSLFVHLKARFVNMVLGQITRESIRRALT 388

  Fly   387 GGITAEQIVSYLEQYAHPNM-RMVESAIHSK-----SC------LPPTVVDQIKLWELERNRFTY 439
            .||||:||::|||.:|||.| |:.|..:..|     :|      |||||||||:||:||.:|...
Yeast   389 NGITADQIIAYLETHAHPQMRRLAEEKLEKKLELDPNCKEPLQVLPPTVVDQIRLWQLELDRVIT 453

  Fly   440 TEGVLYNQFLSHTDFVTLRDYAQSIHMLVWQNERTRTMVVQKNGHDDV----KRYWKK 493
            .||.||:.|.:..::..|..|||.|.:|:|::::.:...:.|.|:..|    ||..||
Yeast   454 YEGSLYSDFETSQEYNLLSKYAQDIGVLLWKDDKKKKFFISKEGNSQVLDFAKRKLKK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mrn	NP_648780.1	Tfb2	39..404	CDD:461075	135/406 (33%)
		Tfb2_C	425..492	CDD:465701	25/70 (36%)
TFB2	NP_015203.1	Tfb2	9..510	CDD:470994	173/510 (34%)