DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dop and DBF20

DIOPT Version :9

Sequence 1:	NP_001261884.1	Gene:	dop / 39686	FlyBaseID:	FBgn0267390	Length:	2139	Species:	Drosophila melanogaster
Sequence 2:	NP_015436.1	Gene:	DBF20 / 856227	SGDID:	S000006315	Length:	564	Species:	Saccharomyces cerevisiae

Alignment Length:	416	Identity:	131/416 - (31%)
Similarity:	201/416 - (48%)	Gaps:	73/416 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   830 PQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADNPF 894
            |:..||.|:..:..|.||.|||.|.|.:.:..|:|.:||..|...|:...|..|||||:...:.:
Yeast   164 PKHKDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDW 228

  Fly   895 VVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSYGIVHRDL 959
            :|.:..:|:..:.|.|.||:|.|||..|||.|...|.:..||||.:|...||..||..|..||||
Yeast   229 LVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDL 293

  Fly   960 KPDNLLITALGHIKLTDFGLS------------KMGLMSLATNLYEGYIDSETRQFSD-KQVY-- 1009
            ||:|.||.|.||||||||||:            |:.|..:....:..:.:   |...| :::|
Yeast   294 KPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTE---RSIEDRRKIYHN 355

  Fly  1010 -------------GTPEYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHT- 1060
                         |:|:|:|.||:..:.|...||:||:|.:|:|.|:|..||.|.:|.|.:.:.
Yeast   356 MRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLR 420

  Fly  1061 -VNDDIEWPDSED---------WPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDW 1115
             ....:..|.:||         |       |:|::|: .:|.:|:.:..   ::::..||..:::
Yeast   421 YWKKTLRRPRTEDRRAAFSDRTW-------DLITRLI-ADPINRVRSFE---QVRKMSYFAEINF 474

  Fly  1116 NSLLRQKAEFVPQLSHDDDTSYFDTRMDRYNHDLGGEDTD----------DTDDTPVFGSFNSYT 1170
            .:|......|:|||..:.|..|||   |..|.:...:..|          ..||:.|......:|
Yeast   475 ETLRTSSPPFIPQLDDETDAGYFD---DFTNEEDMAKYADVFKRQNKLSAMVDDSAVDSKLVGFT 536

  Fly  1171 PQYR--KQH-----YSWSRHATPTST 1189
            .::|  ||.     |:.|.|:.|.||
Yeast   537 FRHRDGKQGSSGILYNGSEHSDPFST 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dop	NP_001261884.1	DUF1908	344..702	CDD:286070
		STKc_MAST	834..1115	CDD:270760	105/319 (33%)
		S_TKc	835..1110	CDD:214567	102/313 (33%)
		PDZ_signaling	1506..1587	CDD:238492
DBF20	NP_015436.1	STKc_Sid2p_like	157..539	CDD:270751	122/391 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344972
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840