DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dop and AT1G48490

DIOPT Version :9

Sequence 1:	NP_001261884.1	Gene:	dop / 39686	FlyBaseID:	FBgn0267390	Length:	2139	Species:	Drosophila melanogaster
Sequence 2:	NP_001323023.1	Gene:	AT1G48490 / 841270	AraportID:	AT1G48490	Length:	1236	Species:	Arabidopsis thaliana

Alignment Length:	1349	Identity:	328/1349 - (24%)
Similarity:	509/1349 - (37%)	Gaps:	409/1349 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SSSSSTSSNHSVSAVLGSKISTSTPQKNDEHQEQEFINQSVASEIEAMSISDSASAESSSGATAT 85
            |.|||.||::|..:|.......|..:|...:.::|..:.:....:.|.  ...||.|..|.:...
plant    14 SRSSSPSSSNSPRSVGSDSPIRSDKKKPKSNSKEETRSPNTKKHVSAK--GKEASLEVHSSSPGK 76

  Fly    86 ATATMSGSPVPKRHLSTANLSRIRPQSSYSARVLIFDDSDQEAAAAAAALAAASSSCNSSVKSCS 150
            :.::.|||...|....|       |.:|         |..:|:.|:.:.:.|:|...| .:|:.|
plant    77 SNSSSSGSEAKKPITET-------PATS---------DVKEESPASVSPIMASSLGLN-RIKTRS 124

  Fly   151 G---------------LELLPT-SPAKLSIGNDSTNGSSM----MRNLN--LTKSSSGG------ 187
            |               :.:||. ..:||..|......|.:    :|:.|  |..|.:.|
plant   125 GPLPQESFFSFENDYAIPVLPCYKLSKLDTGKKEAGSSKVDIGPLRSSNPALLASGTAGQFKVSP 189

  Fly   188 -LSGSSSSLH-----------------SRGYTALLRKISYQQHTNSLRAVSGETSNLLRMRHSSL 234
             :||...|..                 |..|.||||..|..                 |.|....
plant   190 TISGPEGSAEVCTPENSYDLDDPKESDSPRYQALLRMTSAP-----------------RKRFPGD 237

  Fly   235 GKSAPCLTGNYFRHELTA----PLPVQPPGFGASPLGGHNISRSGSCAGI--------GLAKHHH 287
            .||        |.|||.:    |.|:..|            .|..:...|        ..||...
plant   238 IKS--------FSHELNSKGVRPFPLWKP------------RRLNNLEDILNLIRTKFDKAKEEV 282

  Fly   288 HHHLHGVVMRGSAGGGAGSGGGSSSGVAHHRLSLVTNSAAVAAAGGSRTHSPYSASPVDSPRLNS 352
            :..|.       |.||........:..:|..|.:......|.|...::|.|
plant   283 NSDLF-------AFGGDLLDIYDKNKESHPELLVTIEDLLVLAKTCAKTTS-------------- 326

  Fly   353 PMPFAFAPIKRI-ASCRGVVADGRRWSVASLPSSGYGTTPGSSNLSSQCSSQEGLNQLAHNIPPG 416
                     |.. ..|.|:|.|                                |:.....:|||
plant   327 ---------KEFWLQCEGIVQD--------------------------------LDDRRQELPPG 350

  Fly   417 VQEADAAAVAAGACCAEHLKQHCPKHCALLLAVSQ--------KQLTPQPPKPTQLQPQKSMTAA 473
            |                 |||   .|..:|..:::        |:...|.....||:....:.:|
plant   351 V-----------------LKQ---LHTRMLFILTRCTRLLQFHKESWGQEEDAVQLRQSGVLHSA 395

  Fly   474 CVNCCAELSVTCGGQQAGGGAANGGSSANSSGSSAMQVGGRMSPY------------FRPRSRSL 526
                         .::...|....|.  .||.::|::|......|            |..|...|
plant   396 -------------DKRDPTGEVRDGK--GSSTANALKVPSTKKAYSQEQRGLNWIEGFFVRPAPL 445

  Fly   527 SSP-------SRSP--------------------------------------IVDNEIAVMNTLY 546
            |||       |.||                                      :|...:|:.:.:.
plant   446 SSPYNETSKDSESPANIDKMSSWKRLPSPASKGVQEAAVSKEQNDRKVEPPQVVKKLVAISDDMA 510

  Fly   547 KERFP-----KATQQMEERLK-----------LFINENKSAACNSFRDSQPIVRFVHHQVLEMAR 595
            ..:.|     ||:|:...:.:           ..|:|..|..|....:..|......|     :|
plant   511 VAKLPEVSSAKASQEHMSKNRHNISWGYWGHQSCISEESSIICRICEEEIPTTHVEDH-----SR 570

  Fly   596 DC--LHKSEAKLI-TSQYFYELSENLERLLVETKEK-------SPEAAAELNGVIKKLLLIISRP 650
            .|  ..|.:.|.: ..:....::..||::.....:|       |||.....|..:.:.|.::|..
plant   571 ICALADKYDQKGVGVDERLMAVAVTLEKITDNVIQKDSLAAVESPEGMKISNASLTEELDVLSPK 635

  Fly   651 AR---------LLECL----------------------EFDPQEFYELLEAAEGH---AKAMPVI 681
            ..         :|:|.                      .|.|:....:..::.|.   ...:|..
plant   636 LSDWSRRGSEDMLDCFPETDNSVFMDDMGCLPSMSCRTRFGPKSDQGMATSSAGSMTPRSPIPTP 700

  Fly   682 KADIPQYIIHKLGL--NRDPIAELQQELRETQQMCSEQVTVDADPLHPGGSLLLNSPLTSAAKQL 744
            :.|..:.::...|.  ::|...:: .||.:..:..:..:.||...:.     ||.|.|......:
plant   701 RPDPIELLLEGKGTFHDQDDFPQM-SELADIARCAANAIPVDDQSIQ-----LLLSCLEDLRVVI 759

  Fly   745 SSLALDAIAMDSGSGTATPQQPPQTPVATCDTAPSFALAISQMNEEKGG--------SSSAVGGG 801
            .....||:.::: .||...:...:..:..|:.          |::|||.        ....|...
plant   760 DRRKFDALIVET-FGTRIEKLIQEKYLQLCEL----------MDDEKGTIIDEDAPLEDDVVRSL 813

  Fly   802 SSSKVAGAEGITGGSAATATGSGAQQPSPQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKI 866
            .:|.|...:.|:                  .:||:::|.||.||:|.|.|.:..||...||:|.:
plant   814 RTSPVHLRDRIS------------------IDDFEVMKSISRGAFGHVILARKNTTGDLFAIKVL 860

  Fly   867 NKNNLILRNQVEQVFAERDILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLP 931
            .|.::|.:|.||.:.||||||..|.|||||..:.||...::|.|||||:.|||..::|:.||.|.
plant   861 RKADMIRKNAVESILAERDILINARNPFVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCLD 925

  Fly   932 ADMARFYFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYI 996
            ...||.|.||.|||:|||||.|:||||||||||||...||:|||||||||:||::...:| .|.:
plant   926 EANARVYIAEVVLALEYLHSEGVVHRDLKPDNLLIAHDGHVKLTDFGLSKVGLINNTDDL-SGPV 989

  Fly   997 DSETRQFSD-----------KQVYGTPEYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFG 1050
            .|.|....:           :...|||:|:|||::|..|:|...||||:||||||||:|..||..
plant   990 SSATSLLVEEKPKLPTLDHKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILYEFLVGIPPFNA 1054

  Fly  1051 ETTEELFAHTVNDDIEWPD-SEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMD 1114
            :..:::|.:.:|.:|:||. .||  :..||:|:|.:||.::|..|||.: ||.|:|:|.:|..:|
plant  1055 DHPQQIFDNILNRNIQWPPVPED--MSHEARDLIDRLLTEDPHQRLGAR-GAAEVKQHSFFKDID 1116

  Fly  1115 WNSLLRQKAEFVPQLSHDDDTSYFDTRMDRYNHDLGGE---DTDDTDDT 1160
            ||:|.:|||.|||...:..|||||.:   ||:.:..||   .|::.:|:
plant  1117 WNTLAQQKAAFVPDSENAFDTSYFQS---RYSWNYSGERCFPTNENEDS 1162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dop	NP_001261884.1	DUF1908	344..702	CDD:286070	70/485 (14%)
		STKc_MAST	834..1115	CDD:270760	138/292 (47%)
		S_TKc	835..1110	CDD:214567	136/286 (48%)
		PDZ_signaling	1506..1587	CDD:238492
AT1G48490	NP_001323023.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	265	1.000	Domainoid score	I458
eggNOG	1	0.900	-	-		E1_KOG0606
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2780
orthoMCL	1	0.900	-	-		OOG6_100724
Panther	1	1.100	-	-	O	PTHR24356
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810