DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dop and AT1G45160

DIOPT Version :9

Sequence 1:	NP_001261884.1	Gene:	dop / 39686	FlyBaseID:	FBgn0267390	Length:	2139	Species:	Drosophila melanogaster
Sequence 2:	NP_001077679.1	Gene:	AT1G45160 / 841084	AraportID:	AT1G45160	Length:	1067	Species:	Arabidopsis thaliana

Alignment Length:	1101	Identity:	276/1101 - (25%)
Similarity:	409/1101 - (37%)	Gaps:	378/1101 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 GYGTTPGSSNLSSQCSSQEGLNQLAHNIPPGVQEADAAAVAAGACCAEHLKQHCPKHCALLLAVS 450
            |:|.|.|||.                      ||      ..|...:..|..:.||:..
plant    58 GHGRTTGSSK----------------------QE------RKGTKLSRWLASYKPKYSC------ 88

  Fly   451 QKQLTPQPPKPTQLQPQKSMTAACVNCCAELSVTCGGQQAGGGAAN--GGSSANSSGSSAMQV-- 511
                  .|||           .||.:..:...:...|:.:|.....  ..|..|...|.:|.:
plant    89 ------HPPK-----------YACSSTTSSEEIKLRGKNSGKDEEKMIKISETNPPCSKSMGIKS 136

  Fly   512 --------GGRMSPYFRPRSRSLSSPSRSPIVDNEIAVMNTLYKERFPKATQQMEERLKLFINEN 568
                    ||..:||.||.|.            |::..:......||..|.:.::::|.:|:.:.
plant   137 FSHELGPRGGVQTPYPRPHSY------------NDLKELLGSLHSRFDVAKETVDKKLDVFVRDV 189

  Fly   569 KSAACNSFRDSQPIVRFVHHQVLEMARDCLHKSEAKLITSQYFYELSENLERLLVETKEKSPEAA 633
            |. |......|.|..|.:..|:|::||.|:..:.|         :|....|.::.:...|..:..
plant   190 KE-AMEKMDPSCPEDREMAEQLLDVARACMEMTSA---------QLRATCESIVQDLTRKRKQCQ 244

  Fly   634 AELNGVIK----KLLLIISRPARLL------------------ECLEFDP--------------- 661
            |   |::|    :||.|::...|::                  ||||..|
plant   245 A---GLVKWLFSQLLFILTHCTRVVMFQKETEPIDESSFRKFKECLERIPALETDWGSTPRVDDS 306

  Fly   662 -------------QEF----YELLE-----------------AAEGHAKAMPVIKADIPQY---I 689
                         |:|    .|.||                 |.||:|.|.....:..||:   :
plant   307 GSGYPEYQRNEAGQKFKRRDKESLESETALDYVVPNDHGNNAAREGYAAAKQEFPSHEPQFDSKV 371

  Fly   690 I---------HKLGLNRDPIAELQQELRETQQMCSEQV---------------------TVDADP 724
            :         ::..::.:|..||........::|.|:|                     .||.|.
plant   372 VEQRFYLSDEYEDKMSNEPGKELGGSDYVICRICEEEVPLFHLEPHSYICAYADKCEINCVDVDE 436

  Fly   725 ---------------------LHPGG---SLLLNSPLTSAA----------KQLSSLALDAIAMD 755
                                 ...||   |:|..|.:.|..          |.|..:..|...||
plant   437 RLLKLEEILEQIIDSRSLNSFTQAGGLENSVLRKSGVASEGCSPKINEWRNKGLEGMFEDLHEMD 501

  Fly   756 ----------------------------SGSGTATPQQPPQTP---------------------- 770
                                        |.:|:.|......||
plant   502 TAFIDESYTYPIHLKSHVGAKFCHHATSSSTGSITSVSSTNTPRTSHFDSYWLERHCPEQEDLRL 566

  Fly   771 ------VATCDTAPSFA---------------LAISQMNEEKGGSSSAVGG-------------- 800
                  :|.|..:..|:               .|:.:..:.|.......||
plant   567 MMDLSDIARCGASTDFSKEGSCDYIMACMQDIQAVLKQGKLKALVIDTFGGRIEKLLCEKYLHAR 631

  Fly   801 ------GSSSKVAGAEGITGGSAATATGSGAQQPSPQ--------ENDFDIVKLISNGAYGAVYL 851
                  .|...:..:|.:...::||          ||        .:||:|:|.||.||:|.|:|
plant   632 ELTADKSSVGNIKESEDVLEHASAT----------PQLLLKDRISIDDFEIIKPISRGAFGKVFL 686

  Fly   852 VKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADNPFVVSMYCSFETKKHLCLVMEYVE 916
            .:.:||...||:|.:.|.::|.:|.:|::..||:||.....||:|..:.||..:.:|.|||||:.
plant   687 ARKRTTGDFFAIKVLKKLDMIRKNDIERILQERNILITVRYPFLVRFFYSFTCRDNLYLVMEYLN 751

  Fly   917 GGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSK 981
            |||..:||:.:|.|..::||.|.||.|||:|||||..|||||||||||||...||||||||||||
plant   752 GGDLYSLLQKVGCLDEEIARIYIAELVLALEYLHSLKIVHRDLKPDNLLIAYNGHIKLTDFGLSK 816

  Fly   982 MGLMSLATNL--YEGYIDSET--RQFSDKQ--------VYGTPEYIAPEVILRQGYGKPVDWWSM 1034
            :||::...:|  :|..:...|  ..|...|        ..|||:|:|||::|...:|...||||.
plant   817 IGLINNTIDLSGHESDVSPRTNSHHFQKNQEEERIRHSAVGTPDYLAPEILLGTEHGYAADWWSA 881

  Fly  1035 GIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQS 1099
            ||:|:|.|.|..||.....|::|.:.:|..:.|||... .:..||:|:|::||...|..|||. :
plant   882 GIVLFELLTGIPPFTASRPEKIFDNILNGKMPWPDVPG-EMSYEAQDLINRLLVHEPEKRLGA-N 944

  Fly  1100 GALEMKEHEYFLGMDWNSLLRQKAEFVPQLSHDDDTSYFDTRMDR-------------YNHDLGG 1151
            ||.|:|.|.:|.|:||.:|..|||.||||....:|||||.:|...             .|.|.|
plant   945 GAAEVKSHPFFQGVDWENLALQKAAFVPQPESINDTSYFVSRFSESSCSDTETGNNSGSNPDSG- 1008

  Fly  1152 EDTDDTDDTPVFGSFNSYTPQYRKQHYSWS----------RHATPTSTDGAKPTGPPPLSS 1202
               |:.|:......|:|  |.|.....::|          .|......|.||..|..|..|
plant  1009 ---DELDECTNLEKFDS--PPYYLSLINFSFKNLSQLASINHDVLLQKDPAKGGGDSPFKS 1064

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dop	NP_001261884.1	DUF1908	344..702	CDD:286070	75/410 (18%)
		STKc_MAST	834..1115	CDD:270760	131/292 (45%)
		S_TKc	835..1110	CDD:214567	128/286 (45%)
		PDZ_signaling	1506..1587	CDD:238492
AT1G45160	NP_001077679.1	S_TKc	670..955	CDD:214567	128/286 (45%)
AT1G45160	NP_001077679.1	STKc_MAST_like	676..960	CDD:270731	127/285 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	265	1.000	Domainoid score	I458
eggNOG	1	0.900	-	-		E1_KOG0606
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2780
orthoMCL	1	0.900	-	-		OOG6_100724
Panther	1	1.100	-	-	O	PTHR24356
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810