DRSC/TRiP Functional Genomics Resources

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Protein Alignment dop and STK32B

DIOPT Version :9

Sequence 1:NP_001261884.1 Gene:dop / 39686 FlyBaseID:FBgn0267390 Length:2139 Species:Drosophila melanogaster
Sequence 2:NP_060871.1 Gene:STK32B / 55351 HGNCID:14217 Length:414 Species:Homo sapiens


Alignment Length:453 Identity:125/453 - (27%)
Similarity:196/453 - (43%) Gaps:83/453 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   828 PSPQEND------FDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDI 886
            |...||:      |.|::.|..|::|.|.:|:.:.|::.:|||.:||...|.|::|..||.|..|
Human    10 PVFDENEEVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQI 74

  Fly   887 LSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHS 951
            :...::||:|:::.||:.::.:.:|::.:.|||....|:..........:.|..|..||:|||..
Human    75 MQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALALEYLQR 139

  Fly   952 YGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIA 1016
            |.|:|||:||||:|:...||:.:|||.::.:             :....|..|   :.||..|:|
Human   140 YHIIHRDIKPDNILLDEHGHVHITDFNIATV-------------VKGAERASS---MAGTKPYMA 188

  Fly  1017 PEVI-----LRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDI-------EWPD 1069
            |||.     ...||..||||||:||..||.|.|..|:      |:.:.|..|:|       ....
Human   189 PEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRPY------EIHSVTPIDEILNMFKVERVHY 247

  Fly  1070 SEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQ--KAEFVPQLSHD 1132
            |..|.....|  ::.:||.::|..|:   |...:::...|...|:|:::.::  ...|||     
Human   248 SSTWCKGMVA--LLRKLLTKDPESRV---SSLHDIQSVPYLADMNWDAVFKKALMPGFVP----- 302

  Fly  1133 DDTSYFDTRMDRYNHDLGGEDTDDTDDTPVFGSFNSYTPQYRKQHYSWSRHATPTSTDGAKPTGP 1197
                    ...|.|.|            |.| .......:.:..|....|.|...|.||.|.:  
Human   303 --------NKGRLNCD------------PTF-ELEEMILESKPLHKKKKRLAKNRSRDGTKDS-- 344

  Fly  1198 PPLSSLPSRAQETPAATVGATSTGALPKLKSGMGSGS-----GSGSGSGSGSASHDGVVNKFL 1255
            .||:.......||........:.   .||:...|.||     .|..|..:.|...||..|..|
Human   345 CPLNGHLQHCLETVREEFIIFNR---EKLRRQQGQGSQLLDTDSRGGGQAQSKLQDGCNNNLL 404

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dopNP_001261884.1 DUF1908 344..702 CDD:286070
STKc_MAST 834..1115 CDD:270760 90/298 (30%)
S_TKc 835..1110 CDD:214567 88/286 (31%)
PDZ_signaling 1506..1587 CDD:238492
STK32BNP_060871.1 STKc_Yank1 22..283 CDD:270730 88/287 (31%)
S_TKc 23..270 CDD:214567 86/270 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 374..396 6/21 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154023
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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