Protein Alignment dop and mastl

DIOPT Version :10

• Sequence 1: NP_648778.1
• Gene: dop / 39686
• FlyBaseID: FBgn0267390
• Length: 2139
• Species: Drosophila melanogaster
• Sequence 2: XP_021325814.1
• Gene: mastl / 445215
• ZFINID: ZDB-GENE-040801-128
• Length: 867
• Species: Danio rerio
• Alignment Length: 861
• Identity: 144/861 - (16%)
• Similarity: 214/861 - (24%)
• Gaps: 545/861 - (63%)

  Fly   815 GSAATATGSGAQQPSPQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQ 879
            |.|..::.|..:.||.:  ||.:||.||.||:|.|||.:.|...:.:|:|.:.|..::.:|..||
Zfish     5 GLACESSNSAVKAPSIE--DFVLVKPISRGAFGKVYLARKKCNSKLYAIKVVKKAEMVDKNMTEQ 67

  Fly   880 VFAERDILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVL 944
            :.||||.|:.:.:||:|.::.|.:|...:.|||||:.|||..:||...|....||:..|.:|..|
Zfish    68 MRAERDALALSKSPFIVHLFYSLQTATKVYLVMEYLIGGDVKSLLHIYGYFDEDMSLKYISEVAL 132

  Fly   945 AVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGL------------------------- 984
            |::|||.:.|:||||||||:||:..||||||||||||:.|
Zfish   133 ALDYLHRHSIIHRDLKPDNMLISNEGHIKLTDFGLSKVKLDRELNLMDILTTPSLVKPTKDYFRT 197

  Fly   985 ----------MSLATNLYEG----------------------------------YI--------- 996
                      :.|.|.:.||                                  |:
Zfish   198 PGQVLSLISSLGLNTPVIEGKRHSSTVLGSPMSCGKVKQRNRSLGSPLMKRRAEYMNSPVCTSRA 262

  Fly   997 --------------------------------------------DSET----------------- 1000
                                                        |||.
Zfish   263 LASNSVFSPVLLARSLTPRLLKSGKRLDTMSVGSTHSCMLPSTTDSENCVSPMWEDEQNLHDVEN 327

  Fly  1001 ----------------------------------------------------------------- 1000
                                                                             
Zfish   328 IPQLNGREVDNRKSRNVPLTPVEKRKTLPARVQDHSTVFTPLNNQVNNSRNIKPDLSAKRLQFGA 392

  Fly  1001 ----------------------------------------------------------------- 1000
                                                                             
Zfish   393 TDNSATKLEKTVPHQSVGNGLIKPEPLKELKSSVKRTFEEVEKSPEQAEILCKKNDAAYKRSFQI 457

  Fly  1001 -----------------------------RQFSDK------------------------------ 1006
                                         :||:::
Zfish   458 PEKTSRAHTGLTGIFSIVGLDDVKSAPKCQQFNERTGPKQSSPIAVAKNLFCELEDQGEEGGKAE 522

  Fly  1007 ----------------------------------------------------------------- 1006
                                                                             
Zfish   523 PNSSSSTSPGDERNIRRSLSLESDVSAHEMSLVANTPQKLSDAKQEVLSSSFEELDENEISAVTP 587

  Fly  1007 ----------------------------------------------------------------- 1006
                                                                             
Zfish   588 MARPTVATPKHSSAKQRRGECERSLLDHPHGLSDSMIKSPGFLKPKNVVAFRSYCSSINRSCTSH 652

  Fly  1007 ----------------------------------------------------------------- 1006
                                                                             
Zfish   653 LSLASFDAMEMSASASFHNAVTPVQKKRPSLNNSLYQTPQQMVVSHTPYRTPKSVRRGPERVEGA 717

  Fly  1007 QVYGTPEYIAPEVILRQGYGKP-----------VDWWSMGIILYEFLIGCVPFFGETTEELFAHT 1060
            .:.|||:|:|||::|    |||           ||||::|:.|:|||.|..||..||.:.:|.:.
Zfish   718 PILGTPDYLAPELLL----GKPHVSGPVRYDFMVDWWALGVCLFEFLTGVPPFNDETPQLVFQNI 778

  Fly  1061 VNDDIEWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQKAEF 1125
            :|.||.|||.|: .:...:::.|..||..:...|.|.:    |:|:|.:|.|:||.:|..|...|
Zfish   779 LNRDIPWPDGEE-ELTPNSRNAIEILLTMDTLKRAGLK----ELKDHPFFDGVDWENLHHQTMPF 838

  Fly  1126 VPQLSHDDDTSYFDTR 1141
            :||..::.|||||:.|
Zfish   839 IPQPDNETDTSYFEAR 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dop	NP_648778.1	DUF1908	344..702	CDD:462637
		STKc_MAST	834..1115	CDD:270760	126/814 (15%)
		PDZ_MAST	1502..1594	CDD:467189
mastl	XP_021325814.1	Protein Kinases, catalytic domain	18..>213	CDD:473864	76/196 (39%)
		Protein Kinases, catalytic domain	<630..858	CDD:473864	56/234 (24%)