DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dop and Stk32c

DIOPT Version :9

Sequence 1:	NP_001261884.1	Gene:	dop / 39686	FlyBaseID:	FBgn0267390	Length:	2139	Species:	Drosophila melanogaster
Sequence 2:	NP_001102392.1	Gene:	Stk32c / 365381	RGDID:	1305864	Length:	488	Species:	Rattus norvegicus

Alignment Length:	416	Identity:	123/416 - (29%)
Similarity:	197/416 - (47%)	Gaps:	67/416 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   754 MDSG------SGTATPQQPP--QTPVATCDTAPSF-ALAISQMNEEKGGSSSA----VGGGSSSK 805
            |.||      |..|.|..||  :...|..|.:|:. ..|.||......|.:.|    :...|..|
  Rat     1 MRSGAERRGSSAAAPPGSPPPGRARPAGSDVSPALPPPAASQPRARDAGDARAQPRPLFQWSKWK 65

  Fly   806 VAGAEGITGGSAATATGSGAQQPSPQEND------FDIVKLISNGAYGAVYLVKHKTTRQRFAMK 864
                   ...|.::.:.|.|::|...:.:      |.|::.|..|::|.|.:|:.:.|.:.:|||
  Rat    66 -------KRMSMSSISASSARRPVFDDKEDVNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMK 123

  Fly   865 KINKNNLILRNQVEQVFAERDILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGP 929
            .:||...|.|::|..||.|.:||...::.|:|:::.||:.::.:.:|::.:.|||....|:....
  Rat   124 YMNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQ 188

  Fly   930 LPADMARFYFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEG 994
            ...|..|.|..|..||::||.|..|:|||:||||:|:...||..||||        ::||.:.:|
  Rat   189 FSEDTVRLYICEMALALDYLRSQHIIHRDVKPDNILLDEQGHAHLTDF--------NIATIIKDG 245

  Fly   995 YIDSETRQFSDKQVYGTPEYIAPEVILR-----QGYGKPVDWWSMGIILYEFLIGCVPF------ 1048
              :..|      .:.||..|:|||:...     .||...|||||:|::.||.|.|..|:
  Rat   246 --ERAT------ALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSN 302

  Fly  1049 FGETTEELFAHTVNDDIEWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGM 1113
            ..|:..:||: ||:  :::..:  |.....|  ::.:||..||..|.   |...:|:.......:
  Rat   303 AVESLVQLFS-TVS--VQYVPT--WSKGMVA--LLRKLLTVNPEHRF---SSLQDMQTAPSLAHV 357

  Fly  1114 DWNSLLRQKAE--FVPQLS--HDDDT 1135
            .|:.|..:|.|  |||...  |.|.|
  Rat   358 LWDELSEKKVEPGFVPNKGRLHCDPT 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dop	NP_001261884.1	DUF1908	344..702	CDD:286070
		STKc_MAST	834..1115	CDD:270760	91/297 (31%)
		S_TKc	835..1110	CDD:214567	91/285 (32%)
		PDZ_signaling	1506..1587	CDD:238492
Stk32c	NP_001102392.1	STKc_Yank1	93..352	CDD:270730	91/284 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347621
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930