DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dop and Stk32a

DIOPT Version :9

Sequence 1:	NP_001261884.1	Gene:	dop / 39686	FlyBaseID:	FBgn0267390	Length:	2139	Species:	Drosophila melanogaster
Sequence 2:	NP_001178823.1	Gene:	Stk32a / 364858	RGDID:	1308338	Length:	397	Species:	Rattus norvegicus

Alignment Length:	319	Identity:	95/319 - (29%)
Similarity:	169/319 - (52%)	Gaps:	37/319 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   823 SGAQQPSPQEND------FDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVF 881
            :.::.|...||:      |:|::.|..|::|.|.:|:...|::.:|||.:||...:.||:|..||
  Rat     5 TSSKAPVLDENEDVNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVF 69

  Fly   882 AERDILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAV 946
            .|..|:...::||:|:::.||:.::.:.:|::.:.|||....|:.......|..:.:..|..:|:
  Rat    70 KELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFQEDTVKLFICELAMAL 134

  Fly   947 EYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGT 1011
            :||.|..|:|||:||||:|:...||:.:|||.::.|             :..|||..:   |.||
  Rat   135 DYLQSQRIIHRDMKPDNILLDEHGHVHITDFNIAAM-------------LPKETRITT---VAGT 183

  Fly  1012 PEYIAPEVI---LRQGYGKPVDWWSMGIILYEFLIGCVPFF---GETTEELFAHTVNDDIEWPDS 1070
            ..|:|||:.   ...||...|||||:|:..||.|.|..|:.   ..:::|:........:.:|.:
  Rat   184 KPYMAPEMFSSRKESGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVNMFETAIVTYPSA 248

  Fly  1071 EDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQK--AEFVP 1127
              |  .||...::.:||:.||..|.   |...:::...|...|:|:::|:::  ..|||
  Rat   249 --W--SAEMVSLLKKLLEPNPDQRF---SHLTDIQNFPYMSDMNWDAVLQKRLIPGFVP 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dop	NP_001261884.1	DUF1908	344..702	CDD:286070
		STKc_MAST	834..1115	CDD:270760	87/292 (30%)
		S_TKc	835..1110	CDD:214567	85/280 (30%)
		PDZ_signaling	1506..1587	CDD:238492
Stk32a	NP_001178823.1	STKc_Yank1	22..281	CDD:270730	85/281 (30%)
Stk32a	NP_001178823.1	S_TKc	23..270	CDD:214567	84/269 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347608
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930