DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dop and Stk32b

DIOPT Version :9

Sequence 1:	NP_001261884.1	Gene:	dop / 39686	FlyBaseID:	FBgn0267390	Length:	2139	Species:	Drosophila melanogaster
Sequence 2:	NP_001100694.1	Gene:	Stk32b / 305431	RGDID:	1306173	Length:	414	Species:	Rattus norvegicus

Alignment Length:	326	Identity:	97/326 - (29%)
Similarity:	162/326 - (49%)	Gaps:	59/326 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   828 PSPQEND------FDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDI 886
            |...||:      |.|::.|..|::|.|.:|:.:.|::.:|||.:||...:.|::|..||.|..|
  Rat    10 PVFDENEEVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCVERDEVRNVFRELQI 74

  Fly   887 LSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHS 951
            :...::||:|:::.||:.::.:.:|::.:.|||....|:..........:.|..|..||:|||..
  Rat    75 MQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGAVKLYVCELALALEYLQR 139

  Fly   952 YGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIA 1016
            |.|:|||:||||:|:...||:.:|||        ::||.|      ..|.:.|  .:.||..|:|
  Rat   140 YHIIHRDIKPDNILLDEHGHVHITDF--------NIATVL------KGTEKAS--SMAGTKPYMA 188

  Fly  1017 PEVIL-----RQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDI----------- 1065
            ||:..     ..||..||||||:|:..||.|.|..|:      |:.:.|..|:|
  Rat   189 PEIFQVYVDGGPGYSYPVDWWSLGVTAYELLRGWRPY------EIHSATPVDEILNMFKVERVHY 247

  Fly  1066 --EWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQ--KAEFV 1126
              .|.:.        ..|::.:||.::|..||   |...:::...|...|:|:::..:  ...||
  Rat   248 SSTWCEG--------MVDLLKKLLTKDPEIRL---SSLRDIQSMTYLADMNWDAVFNKALMPGFV 301

  Fly  1127 P 1127
            |
  Rat   302 P 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dop	NP_001261884.1	DUF1908	344..702	CDD:286070
		STKc_MAST	834..1115	CDD:270760	90/304 (30%)
		S_TKc	835..1110	CDD:214567	88/292 (30%)
		PDZ_signaling	1506..1587	CDD:238492
Stk32b	NP_001100694.1	STKc_Yank1	22..283	CDD:270730	88/293 (30%)
Stk32b	NP_001100694.1	S_TKc	23..272	CDD:214567	87/281 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347618
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930