DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dop and Stk32a

DIOPT Version :9

Sequence 1:	NP_001261884.1	Gene:	dop / 39686	FlyBaseID:	FBgn0267390	Length:	2139	Species:	Drosophila melanogaster
Sequence 2:	NP_848864.1	Gene:	Stk32a / 269019	MGIID:	2442403	Length:	398	Species:	Mus musculus

Alignment Length:	322	Identity:	94/322 - (29%)
Similarity:	169/322 - (52%)	Gaps:	39/322 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   822 GSGAQQPSP--QEND------FDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVE 878
            |:.....:|  .||:      |:|::.|..|::|.|.:|:...|::.:|||.:||...:.||:|.
Mouse     2 GANTSSKAPVFDENEDVNFDHFEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVR 66

  Fly   879 QVFAERDILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETV 943
            .||.|..|:...::||:|:::.||:.::.:.:|::.:.|||....|:.......|..:.:..|..
Mouse    67 NVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFQEDTVKLFICELA 131

  Fly   944 LAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQV 1008
            :|::||.|..|:|||:||||:|:...||:.:|||.::.|             :..|||..:   |
Mouse   132 MALDYLQSQRIIHRDMKPDNILLDEHGHVHITDFNIAAM-------------LPKETRITT---V 180

  Fly  1009 YGTPEYIAPEVILRQ---GYGKPVDWWSMGIILYEFLIGCVPFF---GETTEELFAHTVNDDIEW 1067
            .||..|:|||:...:   ||...|||||:|:..||.|.|..|:.   ..:::|:........:.:
Mouse   181 AGTKPYMAPEMFTSRKETGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVNMFETAIVTY 245

  Fly  1068 PDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQK--AEFVP 1127
            |.:  |  ..|...::.:||:.||..|.   |...:::...|...|:|:::|:::  ..|:|
Mouse   246 PSA--W--SQEMVSLLKKLLEPNPDQRF---SHLTDIQNFPYMSDMNWDAVLQKRLIPGFIP 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dop	NP_001261884.1	DUF1908	344..702	CDD:286070
		STKc_MAST	834..1115	CDD:270760	86/292 (29%)
		S_TKc	835..1110	CDD:214567	84/280 (30%)
		PDZ_signaling	1506..1587	CDD:238492
Stk32a	NP_848864.1	STKc_Yank1	22..281	CDD:270730	84/281 (30%)
		S_TKc	23..270	CDD:214567	83/269 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	379..398
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844246
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930