DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dop and Sgk1

DIOPT Version :9

Sequence 1:	NP_001261884.1	Gene:	dop / 39686	FlyBaseID:	FBgn0267390	Length:	2139	Species:	Drosophila melanogaster
Sequence 2:	NP_001155317.2	Gene:	Sgk1 / 20393	MGIID:	1340062	Length:	524	Species:	Mus musculus

Alignment Length:	318	Identity:	108/318 - (33%)
Similarity:	176/318 - (55%)	Gaps:	22/318 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   825 AQQPSPQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDI-LS 888
            :..|..:.:||..:|:|..|::|.|.|.:||.....:|:|.:.|..::.:.:.:.:.:||:: |.
Mouse   181 SSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLK 245

  Fly   889 FADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSYG 953
            ...:||:|.::.||:|...|..|::|:.||:....|:.........||||.||...|:.||||..
Mouse   246 NVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 310

  Fly   954 IVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIAPE 1018
            ||:|||||:|:|:.:.|||.||||||.|..:....|          |..|.     |||||:|||
Mouse   311 IVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGT----------TSTFC-----GTPEYLAPE 360

  Fly  1019 VILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSEDWPVQAEAKDII 1083
            |:.:|.|.:.||||.:|.:|||.|.|..||:...|.|::.:.:|..::...:    :...|:.::
Mouse   361 VLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPN----ITNSARHLL 421

  Fly  1084 SQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQK--AEFVPQLSHDDDTSYFD 1139
            ..|||::...|||.:...:|:|.|.:|..::|:.|:.:|  ..|.|.:|...|..:||
Mouse   422 EGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFD 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dop	NP_001261884.1	DUF1908	344..702	CDD:286070
		STKc_MAST	834..1115	CDD:270760	98/281 (35%)
		S_TKc	835..1110	CDD:214567	96/275 (35%)
		PDZ_signaling	1506..1587	CDD:238492
Sgk1	NP_001155317.2	STKc_SGK1	183..521	CDD:270753	108/316 (34%)
Sgk1	NP_001155317.2	S_TKc	191..448	CDD:214567	96/275 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844258
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840