Protein Alignment dop and mast3b

DIOPT Version :10

• Sequence 1: NP_648778.1
• Gene: dop / 39686
• FlyBaseID: FBgn0267390
• Length: 2139
• Species: Drosophila melanogaster
• Sequence 2: XP_009304191.2
• Gene: mast3b / 100535762
• ZFINID: ZDB-GENE-111209-1
• Length: 1456
• Species: Danio rerio
• Alignment Length: 1868
• Identity: 683/1868 - (36%)
• Similarity: 879/1868 - (47%)
• Gaps: 582/1868 - (31%)

  Fly   325 SAAVAAAGGSRTHSPYSA-----SPVDSPR--------LNSPMPFAFAPIKRIASCRGVVADGRR 376
            |..|.....:|..||.||     ||:||||        ||  .|||     |....|...|:|||
Zfish    52 SLGVGTPSPTRPLSPLSAHTAASSPLDSPRNVSTAICSLN--FPFA-----RSHLARADRAEGRR 109

  Fly   377 WSVASLPSSGYGTTPGSSNLSSQCSSQEGLNQLAHNIPPGVQEADAAAVAAGACCAEHLKQHCPK 441
            ||:||||||||||.|.||.:||..||||.|:||
Zfish   110 WSLASLPSSGYGTNPPSSTVSSSSSSQERLHQL-------------------------------- 142

  Fly   442 HCALLLAVSQKQLTPQPPKPTQ---------LQPQKSMTAACVNCCAELSVTCGGQQAGGGAANG 497
                            |.:|||         .:..:|||
Zfish   143 ----------------PYQPTQDELHFLFKHFRSSESMT-------------------------- 165

  Fly   498 GSSANSSGSSAMQVGGRMSPYFRPRSRSLSSPSRSPIVDNEIAVMNTLYKERFPKATQQMEERLK 562
                        ...||.|.:.||||||||........||||.:||.:|||||||||.||||||.
Zfish   166 ------------DEDGRPSTFIRPRSRSLSPGRTGGSFDNEIIMMNHVYKERFPKATAQMEERLL 218

  Fly   563 LFINENKSAACNSFRDSQPIVRFVHHQVLEMARDCLHKSEAKLITSQYFYELSENLERLLVETKE 627
            ..|......:.....|.  ::.|:.||::|:|||||.||:..||||.||.||.:.||::|.|..:
Zfish   219 DIIRHFSPDSTLPLGDG--VLGFIQHQLVELARDCLDKSQKGLITSLYFIELQDKLEKMLHEALD 281

  Fly   628 KS-PEAAAELNGVIKKLLLIISRPARLLECLEFDPQEFYELLEAAEGHAKAMPVIKADIPQYIIH 691
            :| .|..:.:..:|||:|:||||||||||||||||:|||.||||||||||....||.|||:|||.
Zfish   282 RSESEEVSIITQLIKKILIIISRPARLLECLEFDPEEFYHLLEAAEGHAKVGQGIKTDIPRYIIS 346

  Fly   692 KLGLNRDPIAELQQELRETQQMCSEQVTVDADPLHPGGSLLLNSPLTSAAKQLSSLALDAIAMDS 756
            :||||.||:.|:.|        ..||                                    .||
Zfish   347 QLGLNWDPLDEVVQ--------LEEQ------------------------------------FDS 367

  Fly   757 GSGTATPQQPPQTPVATCDTAPSFALAISQMNEEKGGSSSAVGGGSSSKVAGAEGITGGSAATAT 821
            |            |..|.|         ||.:.|:...|:.:
Zfish   368 G------------PTLTVD---------SQESAEQNKVSTPL----------------------- 388

  Fly   822 GSGAQQPSPQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDI 886
                 :..|.|:||:.:|||||||||||:||:||.|||||||||||:.|||||||::|||.||||
Zfish   389 -----RRKPLESDFETLKLISNGAYGAVHLVRHKETRQRFAMKKINRQNLILRNQIQQVFVERDI 448

  Fly   887 LSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHS 951
            |:||:|||||||:|||||::|||:||||||||||.|||||:||||.||.|.||||||||:|||||
Zfish   449 LTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMTRMYFAETVLALEYLHS 513

  Fly   952 YGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIA 1016
            ||||||||||||||||::||||||||||||:|||::.||||||:|:.:||:|.||||.|||||||
Zfish   514 YGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMNMTTNLYEGHIEKDTREFIDKQVCGTPEYIA 578

  Fly  1017 PEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSEDWPVQAEAKD 1081
            ||||||||||||||||:|||||||||:|||||||:|.||||...|:|:|.|||.:| .:..:|:|
Zfish   579 PEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVVSDEIIWPDGDD-ALPVDAQD 642

  Fly  1082 IISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQKAEFVPQLSHDDDTSYFDTRMDRYN 1146
            :|::||.|:|.:|||| .||.|:|:|.:|.|:|||.||||||||:|||..:|||||||||.:||:
Zfish   643 MITRLLNQSPLERLGT-GGAPEVKQHMFFSGLDWNGLLRQKAEFIPQLEGEDDTSYFDTRSERYH 706

  Fly  1147 HDLGGED--TDDTDDTPVFGSFNSYTPQYRKQHYSWSRHATPTSTDGAKPTGPPPLSSLPSRAQE 1209
            |....||  |:|.:.:.....|:|::.::.|.:.|....|||::.
Zfish   707 HLASDEDEETNDEESSLEIRRFSSWSNRFSKVYSSTEHLATPSNL-------------------- 751

  Fly  1210 TPAATVGATSTGALPKLKSGMGSGSGSGSGSGSGSASHDGVVNKFLNTPQLRKLDLSSSCLKVPS 1274
                                          |.|...||..                     ::..
Zfish   752 ------------------------------SFSSDRSHSE---------------------EIED 765

  Fly  1275 TPDADYLPELLHNVTIGNDAELRMLKHYLQQPNPGATQRMQQRHSMPPNTTTIISTPATPPPTQT 1339
            ..|..|..|:                  .:|.:.|..:...||.|:.|.|
Zfish   766 RADTHYHGEI------------------QRQASTGDKRLSAQRASLRPRT--------------- 797

  Fly  1340 QATMAATPPTATVGSFSRSTPESSQTDSDDFSPQINRKRKGVCARDILPRFSISIEDET------ 1398
                          |.|.|.||.:      .||.:......:   :.:|||::|.:||.
Zfish   798 --------------SSSSSQPERA------VSPLVVSSTHSL---EAMPRFALSTDDEAEVVVSN 839

  Fly  1399 -----ISAGSSSTENMNLPREQ-SPLALQHQPKSMDGSTSGSSVKHHRS--RSIVKSASALGLSL 1455
                 :.:.|:.|::.: |||| .|....:|.::.|        |...|  |.:.||||...|||
Zfish   840 LRRIRLRSNSTGTKHSS-PREQGGPPCFGNQLETPD--------KQRLSPGRKVPKSASVSTLSL 895

  Fly  1456 MTSLDNSQLAAQLCGIQSPGGGGNGSSTASSRDTSPCRELSPLVTNLKPPIIIRRGPRGFGFTVH 1520
            :.:.|:...:.|...| ||   .:.||..||||:||.|:||..::.|:|||||....:.||||:.
Zfish   896 IITPDDGSGSLQGRSI-SP---RSFSSNPSSRDSSPNRDLSLSISRLRPPIIIHSSGKKFGFTLQ 956

  Fly  1521 TIRVYYGDTDFYTMHHLVMAVDEGSPAFEAGLRPADLITHVNGEAVQGLFHTQVLQLLLSGGEHV 1585
            |||||.|::|.||:||:|..|:|.|||.|||||..|||||||||:||||.||::::|||..|..|
Zfish   957 TIRVYMGNSDIYTIHHMVSGVEESSPAHEAGLRAGDLITHVNGESVQGLVHTEMMELLLKSGNQV 1021

  Fly  1586 TLRATPLEHTSIQSGGRKRDLMQSKLAKKGVNRQKKQTKREHDKKRKTSLFRRISSKRANAEMQQ 1650
            ||:...||.|||:.|..::...:.|:|::..:|.|      .:|.|:.::.:::|.:
Zfish  1022 TLQTIALEDTSIKIGPARKSRCKGKMARRCKSRWK------DNKDRRRNMLKKLSKQ-------- 1072

  Fly  1651 YSAGTSSPTTPSARNLSPLDSSYHSSCCQSAANSSSQSTSPS---SSSPNTPTGSSGSNHGGNAG 1712
                  |....|:|:.|   |..|    .|.::|.|...||:   ||.|.||..|...:|..:.|
Zfish  1073 ------STVMHSSRSFS---SGLH----HSVSSSESLPGSPTHSLSSGPTTPCRSPVPDHTTDTG 1124

  Fly  1713 SVAVAPSALSVQLPSAPPPTQLVLLPHVGAVVGSNPTSVGNVPVSPTGVVPQLYQRPSTLHGLKH 1777
                                    ||...:...|:|:|            |.:..|||:||||..
Zfish  1125 ------------------------LPQNASPCSSSPSS------------PAVQMRPSSLHGLGS 1153

  Fly  1778 KLHAATAVIAGGGNANNPAGGLKTLHTTNNNSLPNRRKSVGHIPLSPLARTPSPSPLPSSPTRSP 1842
            ||          ||......|              ||||...||.||||.|.||..|  ||.|||
Zfish  1154 KL----------GNQRYTKVG--------------RRKSTSSIPPSPLACTSSPQAL--SPQRSP 1192

  Fly  1843 SPLAFPLVGHQPGASNTTQSYSPGSTL--PTLQTAVNANTKKAGFARTKSAE-PSSPLLRRALSP 1904
            |||        |..|.|..|:. |.||  ||:...|         .|.:||| |.||||:|..|.
Zfish  1193 SPL--------PSISKTLHSFH-GKTLSPPTIIRHV---------VRPRSAEPPRSPLLKRVQSA 1239

  Fly  1905 DRL----------HPRSAETKISPLCCSPPIKQPTHQRVVTTTWRSTPGGSASG--AGGAV---- 1953
            ::|          |.....|...|.|                  .....|.|.|  |.|:|
Zfish  1240 EKLSGALFADKKPHAARRHTLEVPHC------------------ELDVSGDAEGEVACGSVYTTD 1286

  Fly  1954 ---LGA----------PSVQPLQLV----------------------PAASEESQRQTAMATVVS 1983
               ||.          ||.:..|:|                      .:..|....||:..|..|
Zfish  1287 HGRLGGYLCAQRLRDWPSERMEQIVVMRKLNLSERRDSFKKQEAVQEVSFDEPDAPQTSAQTGTS 1351

  Fly  1984 TTAAGTDP------SATAVVTLANCEPL-PRIA------EEKDS--PTSTQDSSSVSEGFM---- 2029
            |   ||.|      |.:....:|...|| |:||      ||.|.  ..|.:|.....|..:
Zfish  1352 T---GTRPKHIMGESQSEEECVARRNPLVPQIAVQGSESEEADDWRLCSDEDEDEAEENVLLTRN 1413

  Fly  2030 ---PAIEEFAEGESSSSPTQTLEKPTKVKATEQPEMEP-AGKSKKVDQ 2073
               |.|.     .::.|...|.|....:..|..||..| ..|||.:::
Zfish  1414 QGEPRIH-----TANISSVATCEATGVITVTAMPENHPNPEKSKLINR 1456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dop	NP_648778.1	DUF1908	344..702	CDD:462637	153/375 (41%)
		STKc_MAST	834..1115	CDD:270760	209/280 (75%)
		PDZ_MAST	1502..1594	CDD:467189	55/91 (60%)
mast3b	XP_009304191.2	None