DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dop and stk32a

DIOPT Version :9

Sequence 1:	NP_001261884.1	Gene:	dop / 39686	FlyBaseID:	FBgn0267390	Length:	2139	Species:	Drosophila melanogaster
Sequence 2:	XP_002936753.2	Gene:	stk32a / 100490429	XenbaseID:	XB-GENE-490728	Length:	398	Species:	Xenopus tropicalis

Alignment Length:	304	Identity:	93/304 - (30%)
Similarity:	161/304 - (52%)	Gaps:	33/304 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   833 NDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADNPFVVS 897
            |.|:|::.|..|::|.|.:|:...|::.:|||.:||...:.||:|..||.|..|:...::||:|:
Frog    21 NHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVN 85

  Fly   898 MYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSYGIVHRDLKPD 962
            ::.||:.::.:.:|::.:.|||....|:..........:.|..|..||::||.|..|:|||:|||
Frog    86 LWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVRFTEASVKLYICELALALDYLQSKSIIHRDIKPD 150

  Fly   963 NLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIAPEVILRQG--- 1024
            |:|:...||:.:|||.::.  |:|..|.:              ..|.||..|:|||:...:|
Frog   151 NVLLDEQGHVHITDFNIAT--LVSKGTKI--------------TTVAGTKPYMAPEMFYPRGQIC 199

  Fly  1025 YGKPVDWWSMGIILYEFLIGCVPF--FGETTEELFAHTVND-DIEWPDSEDWPVQAEAKDIISQL 1086
            |...|||||:|:..||.|.|..||  ...|......|..:. .:.:|.:  |  ..|...::.:|
Frog   200 YSFGVDWWSLGVTAYELLRGRRPFHIHSSTAATDIVHVFHTATVTYPPA--W--SEEIVSLLHKL 260

  Fly  1087 LQQNPRDRLGTQSGALE-MKEHEYFLGMDWNSLLRQK--AEFVP 1127
            |.:||.:|.    ..|| :::..|...::|::.|:::  .:|:|
Frog   261 LDRNPEERF----SCLEHIQDFPYLSDVNWDAALQKRLSPQFIP 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dop	NP_001261884.1	DUF1908	344..702	CDD:286070
		STKc_MAST	834..1115	CDD:270760	88/287 (31%)
		S_TKc	835..1110	CDD:214567	87/281 (31%)
		PDZ_signaling	1506..1587	CDD:238492
stk32a	XP_002936753.2	STKc_Yank1	22..281	CDD:270730	87/282 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000