DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SCCRO and Dcun1d3

DIOPT Version :9

Sequence 1:	NP_001246770.1	Gene:	SCCRO / 39685	FlyBaseID:	FBgn0036510	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001020057.1	Gene:	Dcun1d3 / 309035	RGDID:	1308893	Length:	304	Species:	Rattus norvegicus

Alignment Length:	196	Identity:	80/196 - (40%)
Similarity:	107/196 - (54%)	Gaps:	6/196 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 ELDRKRIEQLFMRYRDPSDPLKIGSQGVIHFLEDLDLKPDSKLVLIIAWKFHAEVQCEFSRDEFI 128
            |...:|:|:||.||:|..:. .|..:|:..|..||.:.|....||::||||.|...|:|:|.||.
  Rat    85 ESSLQRLEELFRRYKDERED-AILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFF 148

  Fly   129 NGMCDLGIDSIDKLKTKLPILEQELNDAGKFKDFYHFTFNYAKD--PGQKGIDLEMAIAYWCIVL 191
            :|...:..||||.:..:.|.|..|.....||||.|.|||.:..|  .||:.:..|:|||.|.:|.
  Rat   149 DGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVF 213

  Fly   192 S-GRFKFLDIWCQFLEEKHK--RAISRDTWNLLLDFATNIDDRMSNYDSEGAWPVLIDDFVEWCQ 253
            : .....||.|..||.|...  :.|||||||:.|:|...|...:|||..:.|||.|.|.||||..
  Rat   214 TQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEM 278

  Fly   254 E 254
            |
  Rat   279 E 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCCRO	NP_001246770.1	UBA_like_SF	11..58	CDD:304366
SCCRO	NP_001246770.1	Cullin_binding	141..252	CDD:281545	47/115 (41%)
Dcun1d3	NP_001020057.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..87		1/1 (100%)
		Cullin_binding	164..276	CDD:397562	46/111 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	285..304
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1418097at2759
OrthoFinder	1	1.000	-	-		FOG0000501
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820