DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SCCRO and SPBC839.03c

DIOPT Version :9

Sequence 1:	NP_001246770.1	Gene:	SCCRO / 39685	FlyBaseID:	FBgn0036510	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001342892.1	Gene:	SPBC839.03c / 2541135	PomBaseID:	SPBC839.03c	Length:	251	Species:	Schizosaccharomyces pombe

Alignment Length:	258	Identity:	76/258 - (29%)
Similarity:	128/258 - (49%)	Gaps:	23/258 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 KKFISLTHTGEQTAIFCLQQNDWKFELASDNYFQNPEYYYRELDRKRIEQLFMRYRDPSDPLKIG 87
            :.|...|.|..:.|:..|::.::.:::|...:.|...   ||...|::..:|.::....|...|.
pombe    10 RAFSKATSTSSKAALSWLKKYNFDYDVAYTKWIQQKS---REEAEKQLNNVFSQFSSKEDKDLIE 71

  Fly    88 SQGVIHFLEDLDLKPDSKLVLIIAWKFHAEVQCEFSRDEFINGMCDLGIDSIDKLKTKLPILEQE 152
            ..|.:.....||:..:....|::::...:....||.|:.|:.|..:|...|:|:|  ||.|.|:.
pombe    72 LDGSVQLFTALDISLEDPETLLVSYFLKSPRMGEFHRESFVEGALNLSTTSLDQL--KLAIKEKV 134

  Fly   153 ---LNDAGKFKDFYHFTFNYAKDPGQKGIDLEMAIAYWCIVLSGRFKFLDIWCQFLEEKH--KRA 212
               .:||...|..|.:|:..|.|.|:|.:...:||.::.|:|...|..||.|..||:...  :::
pombe   135 QVWRSDASLQKAIYIYTYPLACDKGKKTLSTSIAIEFFQILLKDTFPLLDDWIAFLKVSPIIEKS 199

  Fly   213 ISRDTWNLLLDFATNI--DDRMSNYDSEGAWPVLIDDFVEWCQENDHLKEDSSPASGYQQQSS 273
            :.:||||.|.||:..:  |...||||.|||||.|||:||.:.:|:           ||:..||
pombe   200 LPKDTWNELWDFSVFVKSDPNCSNYDFEGAWPTLIDEFVSYYREH-----------GYKNSSS 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCCRO	NP_001246770.1	UBA_like_SF	11..58	CDD:304366	7/34 (21%)
SCCRO	NP_001246770.1	Cullin_binding	141..252	CDD:281545	46/117 (39%)
SPBC839.03c	NP_001342892.1	Cullin_binding	125..240	CDD:308909	46/116 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	77	1.000	Domainoid score	I2415
eggNOG	1	0.900	-	-		E1_KOG3077
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I1538
OMA	1	1.010	-	-		QHG53724
OrthoFinder	1	1.000	-	-		FOG0000501
OrthoInspector	1	1.000	-	-		otm47276
orthoMCL	1	0.900	-	-		OOG6_102228
Panther	1	1.100	-	-	O	PTHR12281
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2084
SonicParanoid	1	1.000	-	-		X1511
TreeFam	1	0.960	-	-
	13	12.860