Protein Alignment AGO2 and AGO10

DIOPT Version :10

• Sequence 1: NP_730054.1
• Gene: AGO2 / 39683
• FlyBaseID: FBgn0087035
• Length: 1217
• Species: Drosophila melanogaster
• Sequence 2: NP_199194.1
• Gene: AGO10 / 834403
• AraportID: AT5G43810
• Length: 988
• Species: Arabidopsis thaliana
• Alignment Length: 949
• Identity: 270/949 - (28%)
• Similarity: 424/949 - (44%)
• Gaps: 139/949 - (14%)

  Fly   335 GRQGQEGGYQQRPSGQQQGGHQQGRQGQEGGYQQRPPGQQPNQTQSQ-------------GQYQS 386
            ||:..:|....|||.:                .::||  .|:||.|.             .....
plant    73 GRKSDQGDVCMRPSSR----------------PRKPP--PPSQTTSSAVSVATAGEIVAVNHQMQ 119

  Fly   387 RGPPQQQQAAPLPLPPQPAGSIKRGTIGKPGQVGINYLDLDLSKMPSVAYH-YDVKIMPERPKKF 450
            .|..:....||.|         ..||:|....|..|:.   |:.:|:...: |||.|.||...|.
plant   120 MGVRKNSNFAPRP---------GFGTLGTKCIVKANHF---LADLPTKDLNQYDVTITPEVSSKS 172

  Fly   451 YRQAF-----EQFRVDQLGGAVLAYDGKASCYSVDKLPLNSQNPEVTVTDR-----NG--RTLRY 503
            ..:|.     ..::...||..:.||||:.|.|:..:||...:...|.:.|.     ||  |...|
plant   173 VNRAIIAELVRLYKESDLGRRLPAYDGRKSLYTAGELPFTWKEFSVKIVDEDDGIINGPKRERSY 237

  Fly   504 TIEIKETGDSTIDLKSLTTYMNDRIFDKPMRAMQCVEVVLASPCHNKAIRVGRSFFKMSDPNNRH 568
            .:.||..  :..::..|..::..:..|.|..|:|.:::||......:...||||||. .|.....
plant   238 KVAIKFV--ARANMHHLGEFLAGKRADCPQEAVQILDIVLRELSVKRFCPVGRSFFS-PDIKTPQ 299

  Fly   569 ELDDGYEALVGLYQAFMLGDRP-----FLNVDISHKSFPISMPMIEYLERFSLKAKINNTTNLDY 628
            .|.:|.|:..|.||:.    ||     .||:|::..:|...:|:||::.:...|..::...: |.
plant   300 RLGEGLESWCGFYQSI----RPTQMGLSLNIDMASAAFIEPLPVIEFVAQLLGKDVLSKPLS-DS 359

  Fly   629 SRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETFEHDGKKVTIAS---YFHSR-N 689
            .|..::..|||:.|..|...:.:   |.|||.||:..|.....|..| :..|:.|   ||... .
plant   360 DRVKIKKGLRGVKVEVTHRANVR---RKYRVAGLTTQPTRELMFPVD-ENCTMKSVIEYFQEMYG 420

  Fly   690 YPLKFPQLHCLNVGSSIKSILLPIELCSIEEGQALNRKDGATQVANMIKYAATSTNVRKRKIMNL 754
            :.::...|.||.||:..|:..||:|.|.|.|||...::....|:..::|........|:..|:..
plant   421 FTIQHTHLPCLQVGNQKKASYLPMEACKIVEGQRYTKRLNEKQITALLKVTCQRPRDRENDILRT 485

  Fly   755 LQYFQHNLDPTISRFGIRIANDFIVVSTRVLSPPQVEYH---SKRFTMVKNGSWRMDGMKFLEPK 816
            :|:..::.||....||:.|:.....|..|:|..|.::||   .::..:.:.|.|.|...|.:...
plant   486 VQHNAYDQDPYAKEFGMNISEKLASVEARILPAPWLKYHENGKEKDCLPQVGQWNMMNKKMINGM 550

  Fly   817 PKAHKCAVLYCDPRSGRKMNYTQ--LNDFGNLIISQGKAVN----ISLDSDVTYRPFTDDERSLD 875
            ..:....|.:  .||.:: |..:  .|:.|.:....|...|    |.:.|   .|| ...|::|.
plant   551 TVSRWACVNF--SRSVQE-NVARGFCNELGQMCEVSGMEFNPEPVIPIYS---ARP-DQVEKALK 608

  Fly   876 TIF----ADLKRSQHDLAIVIIPQFRIS-YDTIKQKAELQHGILTQCIKQFTVERKCNNQTIGNI 935
            .::    ...|..:.:|.:.|:|....| |..:|:..|.:.|:::||.....| .|.:.|.:.|:
plant   609 HVYHTSMNKTKGKELELLLAILPDNNGSLYGDLKRICETELGLISQCCLTKHV-FKISKQYLANV 672

  Fly   936 LLKINSKLNGINHKIKD--DPRLPMMKN--TMYIGADVTHPSPDQREIPSVVGVAASHD-PYGAS 995
            .||||.|:.|.|..:.|  ..|:|::.:  |:..|||||||...:...||:..|.||.| |....
plant   673 SLKINVKMGGRNTVLVDAISCRIPLVSDIPTIIFGADVTHPENGEESSPSIAAVVASQDWPEVTK 737

  Fly   996 YNMQYRLQRGALEEIEDMFSITLEHLR-------------VYKEYRNAYPDHIIYYRDGVSDGQF 1047
            |......|....|.|:|::....:.:|             .:::.....|..||:||||||:|||
plant   738 YAGLVCAQAHRQELIQDLYKTWQDPVRGTVSGGMIRDLLISFRKATGQKPLRIIFYRDGVSEGQF 802

  Fly  1048 PKIKNEELRCIKQACDKV--GCKPKICCVIVVKRHHTRFFPSG--DVTTSNKFNNVDPGTVVDRT 1108
            .::...||..|::||..:  ..:|.:..::|.||||||.|.:.  |..::::..|:.||||||..
plant   803 YQVLLYELDAIRKACASLEPNYQPPVTFIVVQKRHHTRLFANNHRDKNSTDRSGNILPGTVVDTK 867

  Fly  1109 IVHPNEMQFFMVSHQAIQGTAKPTRYNVIENTGNLDIDLLQQLTYNLCHMFPRCNRSVSYPAPAY 1173
            |.||.|..|::.||..||||::|..|:|:.:..|...|.:|.||.|||:.:.||.||||...|||
plant   868 ICHPTEFDFYLCSHAGIQGTSRPAHYHVLWDENNFTADGIQSLTNNLCYTYARCTRSVSIVPPAY 932

  Fly  1174 LAHLVAARGRVYLTGTNRFLDLKKEYAKRTIVPEFMKKN 1212
            .|||.|.|.|.||.                  ||.|:.|
plant   933 YAHLAAFRARFYLE------------------PEIMQDN 953

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AGO2	NP_730054.1	ArgoN	471..543	CDD:465134	19/78 (24%)
		ArgoL1	554..601	CDD:462567	18/51 (35%)
		PAZ	605..719	CDD:239207	34/117 (29%)
		Piwi_ago-like	764..1186	CDD:240015	145/457 (32%)
AGO10	NP_199194.1	PLN03202	131..988	CDD:215631	255/873 (29%)