Protein Alignment AGO2 and aub

DIOPT Version :9

• Sequence 1: NP_730054.1
• Gene: AGO2 / 39683
• FlyBaseID: FBgn0087035
• Length: 1217
• Species: Drosophila melanogaster
• Sequence 2: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Alignment Length: 1007
• Identity: 214/1007 - (21%)
• Similarity: 388/1007 - (38%)
• Gaps: 249/1007 - (24%)

  Fly   308 GHQQGRQ--GQEGGYQQRPS-GQQQG-GHQQGRQGQEGGYQQRPSGQQQGGHQQGRQGQEGGYQQ 368
            |..:||:  ..|......|| ||:.. .|.:|.|...|          .||         ||..|
  Fly    12 GRGRGRKPNNVEANRGFAPSLGQKSDPSHSEGNQASGG----------NGG---------GGDAQ 57

  Fly   369 RPPGQQPNQTQSQGQYQSRGPPQ-----QQQAAPLPLPPQPAGSIKRGTIGKPGQVGINYLDLDL 428
            ..|..:.:...:...::|.|.|:     ::....|.....|..:.|:|.:|....|..||  ..:
  Fly    58 VGPSIEKSSLSAVQMHKSEGDPRGSVRGRRLITDLVYSRPPGMTSKKGVVGTHITVQANY--FKV 120

  Fly   429 SKMPS-VAYHYDVKIMPERPKKFYRQAFEQFRVDQLGGAVLAYDGKASCYSVDKLPLNSQNP--- 489
            .|.|: ..|.|.|...|:......|::|.......|||.:  :|| .:.:.:::......:|
  Fly   121 LKRPNWTIYQYRVDFTPDVEATRLRRSFLYEHKGILGGYI--FDG-TNMFCINQFKAVQDSPYVL 182

  Fly   490 EVTVTDRNGRTLRYTIEIKETGD-STIDLKSLTTYMNDRIFDKPMRAMQCVEVVLASPCHNKAIR 553
            |:....|.|..:.  |:||..|. .:.|.:.... :|..:    .|||:.:::.|
  Fly   183 ELVTKSRAGENIE--IKIKAVGSVQSTDAEQFQV-LNLIL----RRAMEGLDLKL---------- 230

  Fly   554 VGRSFF----KMSDPNNRHELDDGYEALVGLYQAFMLGDRPFLNVDISHKSFPISMPMIEYLERF 614
            |.|.::    |::..|.|.:|..||:..:..::..:|     |..:|.||     :...|.|...
  Fly   231 VSRYYYDPQAKINLENFRMQLWPGYQTSIRQHENDIL-----LCSEICHK-----VMRTETLYNI 285

  Fly   615 SLKAKINNTTNLDYSRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETFEHDGKKV 679
             |...|.::.  ||...|....: |: |:.|...:     :.||::.:.........|:.:..::
  Fly   286 -LSDAIRDSD--DYQSTFKRAVM-GM-VILTDYNN-----KTYRIDDVDFQSTPLCKFKTNDGEI 340

  Fly   680 TIASYFHSR--------NYPLKFPQLHCLNV-GSSIKSILLPIELCSIEEGQALNRKDGATQVAN 735
            :...|:..|        ..||...:....|: |.:.::|::..||     .:|....|.......
  Fly   341 SYVDYYKKRYNIIIRDLKQPLVMSRPTDKNIRGGNDQAIMIIPEL-----ARATGMTDAMRADFR 400

  Fly   736 MIKYAATSTNVRKRKIMNLLQYFQHNLD------PTISRFGIRIANDFIVVSTRVLSPPQVEYHS 794
            .::..:..|.:...:.:..|:.|...|.      .|:..:.|.:.:..:.:..|||.|.::.:.:
  Fly   401 TLRAMSEHTRLNPDRRIERLRMFNKRLKSCKQSVETLKSWNIELDSALVEIPARVLPPEKILFGN 465

  Fly   795 KRFTMVKNGSWRMDGMKFLEPKPKAHKCAVLYCDPRS-------------------------GRK 834
            ::                           :..||.|:                         .|.
  Fly   466 QK---------------------------IFVCDARADWTNEFRTCSMFKNVHINRWYVITPSRN 503

  Fly   835 MNYTQLNDFGNLIISQGKAVNISLDSDVTYRPFTDD-----ERSLDTIFADLKRSQHDLAIVIIP 894
            :..||  :|..:.|....::.:::.:.: |....||     .:::|...|      :|..||::
  Fly   504 LRETQ--EFVQMCIRTASSMKMNICNPI-YEEIPDDRNGTYSQAIDNAAA------NDPQIVMV- 558

  Fly   895 QFRISYDTIKQKAELQHGILTQCIKQFT-VERKCNNQTI-------------------GNILLKI 939
                   .::...|.::    .|||:.| |:|...:|.:                   ..:::::
  Fly   559 -------VMRSPNEEKY----SCIKKRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATKVVIQM 612

  Fly   940 NSKLNGINHKIKDDPRLPMMKNTMYIGADVTHPSPDQREIPSVVGVAASHDP-----YGASYNMQ 999
            |:||.|...::.    :| :...|.:|.||.| ||..:. .|.....|:.|.     |.::.|..
  Fly   613 NAKLMGAPWQVV----IP-LHGLMTVGFDVCH-SPKNKN-KSYGAFVATMDQKESFRYFSTVNEH 670

  Fly  1000 YRLQRGALEEIEDMFSITLE-HLRVYKEYRNAYPDHIIYYRDGVSDGQFPKIKNEELRCIKQACD 1063
            .:.|     |:.:..|:.:. .||.|:|...:.|:.|:::||||.|||..::.|.|:..:|...|
  Fly   671 IKGQ-----ELSEQMSVNMACALRSYQEQHRSLPERILFFRDGVGDGQLYQVVNSEVNTLKDRLD 730

  Fly  1064 KV--------GCKPKICCVIVVKRHHTRFFPSGDVTTSNKFNNVDPGTVVDRTIVHPNEMQFFMV 1120
            ::        ||  ::..:||.||.::|:|      |.::  |..||||||..|..|....||:|
  Fly   731 EIYKSAGKQEGC--RMTFIIVSKRINSRYF------TGHR--NPVPGTVVDDVITLPERYDFFLV 785

  Fly  1121 SHQAIQGTAKPTRYNVIENTGNLDIDLLQQLTYNLCHMFPRCNRSVSYPAPAYLAHLVAARGRVY 1185
            |.....||..||.||||.:...|:.|.||.|:|.:.||:...:.::..||..:.||.:|.
  Fly   786 SQAVRIGTVSPTSYNVISDNMGLNADKLQMLSYKMTHMYYNYSGTIRVPAVCHYAHKLAF----- 845

  Fly  1186 LTGTNRFLDLKKEYAKRTIVPEFMKKNPMYFV 1217
                     |..|...|  .|....:|.:||:
  Fly   846 ---------LVAESINR--APSAGLQNQLYFL 866

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AGO2	NP_730054.1	PLN03202	411..1180	CDD:215631	182/856 (21%)
		ArgoN	411..543	CDD:293095	31/136 (23%)
		ArgoL1	554..601	CDD:285861	13/50 (26%)
		PAZ	605..719	CDD:239207	22/122 (18%)
		Piwi_ago-like	764..1186	CDD:240015	110/485 (23%)
aub	NP_476734.1	ArgoN	105..219	CDD:293095	28/121 (23%)
		PAZ_piwi_like	272..392	CDD:239211	26/139 (19%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	115/532 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910