Sequence 1: | NP_730054.1 | Gene: | AGO2 / 39683 | FlyBaseID: | FBgn0087035 | Length: | 1217 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_079128.2 | Gene: | AGO3 / 192669 | HGNCID: | 18421 | Length: | 860 | Species: | Homo sapiens |
Alignment Length: | 846 | Identity: | 272/846 - (32%) |
---|---|---|---|
Similarity: | 415/846 - (49%) | Gaps: | 77/846 - (9%) |
- Green bases have known domain annotations that are detailed below.
Fly 386 SRGPPQQQQAAPLPLPPQPAGSIKRGTIGKPGQVGINYLDLDLSKMPSVAYHYDVKIMPER-PKK 449
Fly 450 FYRQA----FEQFRVDQLGGAVLAYDGKASCYSVDKLPL--NSQNPEVTVTDRNGRTLRYTIEIK 508
Fly 509 ETGDSTIDLKSLTTYMNDRI------FDKPM--RAMQCVEVVLASPCHNKAIRVGRSFFKMSDPN 565
Fly 566 NRHELDDGYEALVGLYQAFMLGDRP-----FLNVDISHKSFPISMPMIEYLERFSLKAKINNTTN 625
Fly 626 LDYSRRFLEPF--------LRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETFE---HDGKKV 679
Fly 680 --TIASYFHSR-NYPLKFPQLHCLNVGSSIKSILLPIELCSIEEGQALNRKDGATQVANMIKYAA 741
Fly 742 TSTNVRKRKIMNLLQYFQHNLDPTISRFGIRIANDFIVVSTRVLSPPQVEYHSKRFTMV--KNGS 804
Fly 805 WRMDGMKF---LEPKPKAHKCAVLYCDPRSGRKMNYTQLNDFGNLIISQGKAVNISLDSDVTYRP 866
Fly 867 FTDDERSLDTIFADLKR--SQHDLAIVIIPQFRISYDTIKQKAELQHGILTQCIKQFTVERKCNN 929
Fly 930 QTIGNILLKINSKLNGINHKIKDDPRLPMMKN-TMYIGADVTHPSPDQREIPSVVGVAASHDPYG 993
Fly 994 ASYNMQYRLQRGALEEIEDMFSITLEHL-RVYKEYRNAYPDHIIYYRDGVSDGQFPKIKNEELRC 1057
Fly 1058 IKQACDKV--GCKPKICCVIVVKRHHTRFFPSGDVTTSNKFNNVDPGTVVDRTIVHPNEMQFFMV 1120
Fly 1121 SHQAIQGTAKPTRYNVIENTGNLDIDLLQQLTYNLCHMFPRCNRSVSYPAPAYLAHLVAARGRVY 1185
Fly 1186 L 1186 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
AGO2 | NP_730054.1 | PLN03202 | 411..1180 | CDD:215631 | 260/813 (32%) |
ArgoN | 411..543 | CDD:293095 | 38/146 (26%) | ||
ArgoL1 | 554..601 | CDD:285861 | 18/51 (35%) | ||
PAZ | 605..719 | CDD:239207 | 38/127 (30%) | ||
Piwi_ago-like | 764..1186 | CDD:240015 | 151/432 (35%) | ||
AGO3 | NP_079128.2 | ArgoN | 73..167 | CDD:406799 | 24/95 (25%) |
ArgoL1 | 177..227 | CDD:400854 | 19/54 (35%) | ||
PAZ_argonaute_like | 228..348 | CDD:239212 | 38/128 (30%) | ||
Piwi_ago-like | 393..818 | CDD:240015 | 151/432 (35%) | ||
Interaction with guide RNA. /evidence=ECO:0000305|PubMed:29040713 | 530..567 | 11/37 (30%) | |||
Interaction with guide RNA. /evidence=ECO:0000305|PubMed:29040713 | 758..805 | 24/46 (52%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG1041 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 1 | 1.010 | - | - | QHG58336 | |
OrthoDB | 1 | 1.010 | - | - | D159407at2759 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0000468 | |
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | O | PTHR22891 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
6 | 5.930 |