Protein Alignment CrebA and Creb3l3

DIOPT Version :10

• Sequence 1: NP_524087.3
• Gene: CrebA / 39682
• FlyBaseID: FBgn0004396
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001012115.1
• Gene: Creb3l3 / 314638
• RGDID: 1308152
• Length: 470
• Species: Rattus norvegicus
• Alignment Length: 227
• Identity: 80/227 - (35%)
• Similarity: 109/227 - (48%)
• Gaps: 23/227 - (10%)

  Fly   301 SNSSDKSHAHGYGIPLTPPSSLPSDDSEGNLSPEHL---FAPLSPNATVSISVANPAGGESSVRV 362
            |:|.|.....|.|.........||...||. .|.:|   ..|..|...|.         ||||.:
  Rat    96 SDSQDTPPGSGPGSANVAARCHPSKQGEGP-CPSYLPSTACPEPPRTQVH---------ESSVAI 150

  Fly   363 S----RTAASITRSSSGSASASGSSTSSTVTT------TRQPIHTPLISSQPKGSTGTLLLTEEE 417
            .    .|........:||.|....:....:.:      .:.|:....:.....|....|:|||:|
  Rat   151 DLDMWSTDTLYPEEQAGSPSRFNLTVKELLLSGGGGDLQQHPLAASQLLGPGSGHCQELVLTEDE 215

  Fly   418 KRTLLAEGYPIPQKLPLTKAEEKSLKKIRRKIKNKISAQESRRKKKEYMDQLERRVEILVTENHD 482
            |:.|..||..:|.:|||||.||:.||||||||:||.||||||:|||||:|.||.|:.....:|.:
  Rat   216 KKLLAKEGVTLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMSACTAQNQE 280

  Fly   483 YKKRLEGLEETNANLLSQLHKLQALVSKHNVK 514
            .::::..||:.|.:||.||..|||||.:...|
  Rat   281 LQRKVLHLEKQNLSLLEQLKHLQALVVQSTSK 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrebA	NP_524087.3	bZIP_CREB3	452..502	CDD:269837	23/49 (47%)
		coiled coil	452..495	CDD:269837	19/42 (45%)
Creb3l3	NP_001012115.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	59..145		14/58 (24%)
		bZIP_CREB3	240..300	CDD:269837	32/59 (54%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	241..270		23/28 (82%)
		coiled coil	242..293	CDD:269837	26/50 (52%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	281..302		7/20 (35%)