Protein Alignment CrebA and ATF6

DIOPT Version :9

• Sequence 1: NP_524087.3
• Gene: CrebA / 39682
• FlyBaseID: FBgn0004396
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: XP_011507610.1
• Gene: ATF6 / 22926
• HGNCID: 791
• Length: 689
• Species: Homo sapiens
• Alignment Length: 453
• Identity: 106/453 - (23%)
• Similarity: 170/453 - (37%)
• Gaps: 139/453 - (30%)

  Fly   119 VPPTHATPIS-----RLSS--NPALNTSVADLTRSSGLQSLQAHQPHHGSGSSHVVVANLEHFQL 176
            |..|..:|.|     ||..  :.||...:...|.:..||...|::.:..:      ..||:
Human     7 VAGTMESPFSPGLFHRLDEDWDSALFAELGYFTDTDELQLEAANETYENN------FDNLD---- 61

  Fly   177 PQHLYDNDCSSSVSSLRDGSMSPDICSDIEIDESAIKDEPMSPDSS--CPASPTSQASSSQHQLS 239
                :|.|.....|.:.|  ::..||:   :.:...:.:|:||.||  ..:||.|..|.|..|
Human    62 ----FDLDLMPWESDIWD--INNQICT---VKDIKAEPQPLSPASSSYSVSSPRSVDSYSSTQ-- 115

  Fly   240 LNLAHLQSEMLFEPKHCGLLLTASSNSNNSLIKSQQRQQQILGQD-NLLMAKMEIKSEKQSTS-- 301
                |:..|           |..||:       ||.....:.|:: |.|.:...:|.:|..|.
Human   116 ----HVPEE-----------LDLSSS-------SQMSPLSLYGENSNSLSSAEPLKEDKPVTGPR 158

  Fly   302 NSSDKSHAHGYGIPLTPPSSLPSDDSEGNLSPEHLFAPLSPNATVSISVANPAGGESSVRVSRTA 366
            |.::..        |||...: ..:|:.::.|:.|..|.:|....:.||  ||         :|.
Human   159 NKTENG--------LTPKKKI-QVNSKPSIQPKPLLLPAAPKTQTNSSV--PA---------KTI 203

  Fly   367 ASITRSSSGSASASGSSTSSTVTTTRQPI--HTPLISSQPKGSTG-TLLLTEEEKRTLLAEGY-- 426
            ...|                  ..|..|:  ..|:||.||..:.| |:||::.....|.|.|.
Human   204 IIQT------------------VPTLMPLAKQQPIISLQPAPTKGQTVLLSQPTVVQLQAPGVLP 250

  Fly   427 ------------------------------PIPQKLPLTKAEEKS-----------LKKIRRKIK 450
                                          |:..||.:||...:|           |::.:|.||
Human   251 SAQPVLAVAGGVTQLPNHVVNVVPAPSANSPVNGKLSVTKPVLQSTMRNVGSDIAVLRRQQRMIK 315

  Fly   451 NKISAQESRRKKKEYMDQLERRVEILVTENHDYKKRLEGLEETNANLLSQLHKLQALVSKHNV 513
            |:.||.:||:||||||..||.|::..::||...||....|:.....::|:..:|:....|..|
Human   316 NRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGTLKRQLDEVVSENQRLKVPSPKRRV 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrebA	NP_524087.3	bZIP_CREB3	452..502	CDD:269837	19/49 (39%)
		coiled coil	452..495	CDD:269837	18/42 (43%)
ATF6	XP_011507610.1	bZIP_ATF6	309..360	CDD:269848	22/50 (44%)
		coiled coil	309..360	CDD:269848	22/50 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144419
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930