Protein Alignment CrebA and CREM

DIOPT Version :9

• Sequence 1: NP_524087.3
• Gene: CrebA / 39682
• FlyBaseID: FBgn0004396
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: XP_024303592.1
• Gene: CREM / 1390
• HGNCID: 2352
• Length: 360
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 83/373 - (22%)
• Similarity: 146/373 - (39%)
• Gaps: 88/373 - (23%)

  Fly   188 SVSSLRDGSMSPDICSDIEIDESAIKDEPMSPDSSCPA-SPTSQASSSQHQLS--LNLAHL---- 245
            :|.|..|||::..:     .:..:...:..:..:|.|| :..|.|.|...:.|  :.|..|
Human    21 TVESQHDGSITASL-----TESKSAHVQTQTGQNSIPALAQVSVAGSGTRRGSPAVTLVQLPSGQ 80

  Fly   246 ----------------QSEMLFEPKHCGLLLTASSNSNNSLIKSQQRQQQILGQDNLLMAKMEIK 294
                            ||..:...:...:..|..|..:..:|.|.:|::.:..:.:......|:.
Human    81 TIHVQGVIQTPQPWVIQSSEIHTVQVAAIAETDESAESEGVIDSHKRREILSRRPSYRKILNELS 145

  Fly   295 SEKQSTSN-SSDKSHAHGYGIPLTPPS----SLPS---DDSEGNLSPEHLFAPLSPNATVSISVA 351
            |:...... ..::|...|     ||||    ::|:   ..|.|.      :..::...|:.||
Human   146 SDVPGVPKIEEERSEEEG-----TPPSIATMAVPTSIYQTSTGQ------YIAIAQGGTIQIS-- 197

  Fly   352 NPAGGESSVRVSRTAASITRSSSGS----------ASASGSSTSSTVTTTRQPI----HTPLISS 402
            ||  |...|   :...::|.::||:          |:.|...|........|.:    .|.|..|
Human   198 NP--GSDGV---QGLQALTMTNSGAPPPGATIVQYAAQSADGTQQFFVPGSQVVVQDEETELAPS 257

  Fly   403 QPKGSTGTLLLTEEEKRT-LLAEGYPI---------PQKLPLTKAEEKSLKKIRRKIKNKISAQE 457
            ....:||.:...:....| .|.:|..:         ||:|    |||.:.|:..|.:||:.:|:|
Human   258 HMAAATGDMPTYQIRAPTAALPQGVVMAASPGSLHSPQQL----AEEATRKRELRLMKNREAARE 318

  Fly   458 SRRKKKEYMDQLERRVEILVTENHDYKKRLEGLEETNANLLSQLHKLQ 505
            .|||||||:..||.||.:|..:|....:.|:.|::.      ..||::
Human   319 CRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDL------YCHKVE 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrebA	NP_524087.3	bZIP_CREB3	452..502	CDD:269837	17/49 (35%)
		coiled coil	452..495	CDD:269837	17/42 (40%)
CREM	XP_024303592.1	pKID	117..154	CDD:308015	5/36 (14%)
		bZIP_CREB1	304..358	CDD:269838	21/59 (36%)
		coiled coil	305..357	CDD:269838	20/57 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930