DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7945 and unc-23

DIOPT Version :9

Sequence 1:	NP_730051.1	Gene:	CG7945 / 39679	FlyBaseID:	FBgn0036505	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_505307.1	Gene:	unc-23 / 179272	WormBaseID:	WBGene00006760	Length:	458	Species:	Caenorhabditis elegans

Alignment Length:	214	Identity:	63/214 - (29%)
Similarity:	103/214 - (48%)	Gaps:	27/214 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 QDLRADAMASSSP--SGSGGGGNGGNSSYGLVDDSRALDRPFNASERFVTILDSLDARVEKLRKD 108
            |:...|....:||  .|....|.....:..:||        |||  :.:..||.::.:||:|||.
Worm   252 QETDGDPSPLTSPITEGKPKRGKKLQRNQSVVD--------FNA--KTIVTLDKIELQVEQLRKK 306

  Fly   109 ALNLQEKKDYLLMSMDLIKSNEMMQNMSEAEREEIILYLQRVSSRLATVELRVRTVRDNSQEDSL 173
            |..|:.:|:.:|.|:..|..:..|..:.|.:||||.....|::.|..||::.|.|.|:..|:.:|
Worm   307 AAELEMEKEQILRSLGEISVHNCMFKLEECDREEIEAITDRLTKRTKTVQVVVETPRNEEQKKAL 371

  Fly   174 SQINVLIDSMIKMGDPVIGRQR-C-QFYLNACCSSSMDPSGHMDTVPEADVGPVDKKFESVLLGC 236
            ....::||.:.:|....|.:.: | |.|:|||..             |...|...:.|..:::.|
Worm   372 EDATLMIDEVGEMMHSNIEKAKLCLQTYMNACSY-------------EETAGATCQNFLKIIIQC 423

  Fly   237 TLDDQKNIKKRLQALMAYL 255
            ..||||.||:||:.||:.:
Worm   424 AADDQKRIKRRLENLMSQI 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7945	NP_730051.1	None
unc-23	NP_505307.1	SMC_prok_B	<275..>452	CDD:274008	57/191 (30%)
unc-23	NP_505307.1	BAG	370..450	CDD:214591	25/86 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166488
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H31233
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1268987at2759
OrthoFinder	1	1.000	-	-		FOG0006323
OrthoInspector	1	1.000	-	-		oto19429
orthoMCL	1	0.900	-	-		OOG6_109431
Panther	1	1.100	-	-	LDO	PTHR12334
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3579
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.970