DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7857 and Otud4

DIOPT Version :9

Sequence 1:	NP_648769.2	Gene:	CG7857 / 39671	FlyBaseID:	FBgn0026738	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_001242962.1	Gene:	Otud4 / 73945	MGIID:	1098801	Length:	1107	Species:	Mus musculus

Alignment Length:	147	Identity:	31/147 - (21%)
Similarity:	65/147 - (44%)	Gaps:	28/147 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 RQLSLHN--IPSDGDCLYQSIRHQLIVNALPGHSVQ---ELREETANYVRAHKDSLISYMIHPET 229
            |:|.|:.  :..||.||::::..|::      ||..   |:|.....|:|.:::...:::
Mouse    30 RKLGLYRKLVAKDGSCLFRAVAEQVL------HSQSRHVEVRMACIRYLRENREKFEAFI----- 83

  Fly   230 GDILNDQQFEQYCHDIAKTHAWGGHIELKAISSLLRVPIEVIQAEG-APTLLGQEEFGGSPLIIC 293
                 :..||:|...:.....|.|.:|:.|:|.:.|....:.|... :|:.:.:..| ...:::|
Mouse    84 -----EGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFVIYQEPNVSPSHVTENNF-PEKVLLC 142

  Fly   294 YHRHIYQLGAHYNSTVP 310
            :..     |.||:...|
Mouse   143 FSN-----GNHYDIVYP 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7857	NP_648769.2	COG5539	17..307	CDD:227826	30/142 (21%)
CG7857	NP_648769.2	OTU	178..305	CDD:280496	25/130 (19%)
Otud4	NP_001242962.1	Cys-loop. /evidence=ECO:0000250\|UniProtKB:Q5VVQ6	39..45		2/5 (40%)
		OTU	42..>121	CDD:303090	20/94 (21%)
		Variable-loop. /evidence=ECO:0000250\|UniProtKB:Q5VVQ6	94..104		2/9 (22%)
		His-loop. /evidence=ECO:0000250\|UniProtKB:Q5VVQ6	143..148		1/9 (11%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	195..239
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	322..431
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	470..568
		T4BSS_DotH_IcmK	558..>644	CDD:289093
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	918..1107
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835254
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840