Protein Alignment CG7857 and Otud6b

DIOPT Version :10

• Sequence 1: NP_648769.2
• Gene: CG7857 / 39671
• FlyBaseID: FBgn0026738
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_690025.3
• Gene: Otud6b / 72201
• MGIID: 1919451
• Length: 294
• Species: Mus musculus
• Alignment Length: 320
• Identity: 122/320 - (38%)
• Similarity: 184/320 - (57%)
• Gaps: 58/320 - (18%)

  Fly     5 DVAIAELESRLDEVSLEDIGARHRRERKDLQAKLQAMKKNAPKNNKNKRKEFLEEMARLEGELEQ 69
            :|...||:   ||   |.:..|||:|:|:||||:|.||...|||:|.:||:..|::|:||.|:||
Mouse     3 EVVAEELD---DE---EQLVRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEREMEQ 61

  Fly    70 RHKAELKAAEAMEAPVLVEPVVKEPAEKPETEVTDDDGIEEKEEQLAPN----------QRVSKA 124
            :|:.||:..:                     ::|..|   .|.:.:|.|          .|:|||
Mouse    62 KHREELEQLK---------------------QLTFKD---SKIDSVAVNISNLVLENQPPRISKA 102

  Fly   125 QKRRDKKA-----KEARAREAEIKTELQNAANQPTPKLIELQQITAKLSQRQLSLHNIPSDGDCL 184
            ||||:|||     :|.|..||||: .|..|.:..:.||.::      |:.|:|.:..|||||.|:
Mouse   103 QKRREKKAALEKEREERIAEAEIE-NLSGARHLESEKLAQI------LAARELEIKQIPSDGHCM 160

  Fly   185 YQSIRHQLIVN--ALPGHSVQELREETANYVRAHKDSLISYMIHPETGDILNDQQFEQYCHDIAK 247
            |.::..||...  ||   :|..||.:||.|::.|.|..:.::.:|.|||:...::|.:||.||..
Mouse   161 YGALEDQLREQDCAL---TVASLRRQTAEYMQTHSDDFLPFLTNPSTGDMYTPEEFGKYCDDIVN 222

  Fly   248 THAWGGHIELKAISSLLRVPIEVIQAEGAPTLLGQEEFGGSPLIICYHRHIYQLGAHYNS 307
            |.||||.:||:|:|.:|:.|||::||:..|.::| ||:..:||::.|.||.|.||.||||
Mouse   223 TAAWGGQLELRALSHILQTPIEILQADAPPIIVG-EEYPRNPLVLVYMRHAYGLGEHYNS 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7857	NP_648769.2	COG5539	17..307	CDD:227826	116/306 (38%)
		OTU_OTUD6	163..309	CDD:438598	62/147 (42%)
Otud6b	NP_690025.3	TOPEUc	<7..80	CDD:214661	35/102 (34%)
		OTU_OTUD6	139..283	CDD:438598	63/153 (41%)
		Cys-loop. /evidence=ECO:0000250	153..159		5/5 (100%)
		Variable-loop. /evidence=ECO:0000250	220..230		6/9 (67%)
		His-loop. /evidence=ECO:0000250	268..278		6/9 (67%)