DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7857 and Otud1

DIOPT Version :9

Sequence 1:	NP_648769.2	Gene:	CG7857 / 39671	FlyBaseID:	FBgn0026738	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_081991.1	Gene:	Otud1 / 71198	MGIID:	1918448	Length:	454	Species:	Mus musculus

Alignment Length:	248	Identity:	64/248 - (25%)
Similarity:	106/248 - (42%)	Gaps:	54/248 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 HKAELKAAEAMEAPVLVEPVVKEPAEKPETEVTDDDGIEEKEEQLA---------PNQRVSKAQK 126
            |:..| ||....||. ..||..||...|.   :...|.|.:.|:.:         .:...|.|.:
Mouse   162 HRQAL-AASQHRAPA-PAPVGPEPGAGPG---SGPWGEERRAERSSRGWDRASGRSDASGSDALR 221

  Fly   127 RRDKKAKEARAREAEIKTELQNAAN---------QPTPK-------LIELQQITAKLSQR-QLSL 174
            |:|.:| ||....|..::..:.|.|         :..|:       |.|:::....|.|| :...
Mouse   222 RQDPEA-EAHPVPAPARSSGEPAQNGEGEAVGTSRADPRDEKLALYLAEVERQDKYLRQRNKYRF 285

  Fly   175 HNIPSDGDCLYQSIRHQLIVNALPGHSVQELREETANYVRAHKDSLISYMIHPETGDILNDQQFE 239
            |.|| ||:|||::: .:.:......|  :||||:|.:|:..|.|. .|.:|..:.|
Mouse   286 HIIP-DGNCLYRAV-SKTVYGDQSLH--RELREQTVHYIADHLDH-FSPLIEGDVG--------- 336

  Fly   240 QYCHDIAKTHAWGGHIELKAISSLLRVPIEV-----IQAEGAPTL---LGQEE 284
            ::....|:..||.|:.||.|:..:|.|.|.:     :::....|:   ||.|:
Mouse   337 EFIIAAAQDGAWAGYPELLAMGQMLNVNIHLTTGGRLESPTVSTMIHYLGPED 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7857	NP_648769.2	COG5539	17..307	CDD:227826	64/248 (26%)
CG7857	NP_648769.2	OTU	178..305	CDD:280496	32/115 (28%)
Otud1	NP_081991.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	36..64
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..257		24/100 (24%)
		Cys-loop. /evidence=ECO:0000250	287..293		4/6 (67%)
		OTU	288..405	CDD:280496	33/116 (28%)
		His-loop. /evidence=ECO:0000250	342..352		4/9 (44%)
		Variable-loop. /evidence=ECO:0000250	399..404
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910