DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7857 and yod1

DIOPT Version :9

Sequence 1:	NP_648769.2	Gene:	CG7857 / 39671	FlyBaseID:	FBgn0026738	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_001017716.1	Gene:	yod1 / 550411	ZFINID:	ZDB-GENE-050417-217	Length:	301	Species:	Danio rerio

Alignment Length:	201	Identity:	45/201 - (22%)
Similarity:	79/201 - (39%)	Gaps:	37/201 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 DKKAKEARAREAEIKTE----LQNAANQPTPKLIELQ------QITAKLSQRQLSLHNIPSDGDC 183
            |.:..||..::..||:.    ::...|:|.|.:....      ::|..:.:|.     :|:|..|
Zfish    54 DLRNGEAHLKDYPIKSGDTLIVEEEKNKPKPPVQPTVTKGPSFEVTPVVERRV-----VPADNSC 113

  Fly   184 LYQSIRHQLIVNALPGHSVQELREETANYVRAHKDSLISYMIHPETGDILNDQQFEQYCHDIAKT 248
            |:.|:.:.:...........|:|...|..| |...:..|..:..:|.        |:||..|.:.
Zfish   114 LFTSVNYVMEGGVYDPACASEMRGLIAQIV-ASDPTAYSEAVLGKTN--------EEYCTWIRRD 169

  Fly   249 HAWGGHIELKAISSLLRVPIEVIQAEGAPTLLGQEEFGGSPLIICYHRHIYQLGAHYN------- 306
            ..|||.||:..:|...:..|.|:..:........|:.|.:..::.    ||. |.||:
Zfish   170 DTWGGAIEVSILSKFYQCEICVVDTQTVRVDRFGEDAGYTKRVLL----IYD-GIHYDPLQKVLP 229

  Fly   307 -STVPA 311
             |.|||
Zfish   230 GSDVPA 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7857	NP_648769.2	COG5539	17..307	CDD:227826	41/195 (21%)
CG7857	NP_648769.2	OTU	178..305	CDD:280496	29/126 (23%)
yod1	NP_001017716.1	UBX-like	5..83		6/28 (21%)
		UBL	5..75	CDD:176364	5/20 (25%)
		COG5539	26..300	CDD:227826	45/201 (22%)
		Cys-loop. /evidence=ECO:0000250\|UniProtKB:Q5VVQ6	107..113		2/5 (40%)
		OTU	108..223	CDD:303090	31/128 (24%)
		Variable-loop. /evidence=ECO:0000250\|UniProtKB:Q5VVQ6	166..176		4/9 (44%)
		His-loop. /evidence=ECO:0000250\|UniProtKB:Q5VVQ6	216..220		2/4 (50%)
		S2 site. /evidence=ECO:0000250\|UniProtKB:Q5VVQ6	244..249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5539
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810