DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7857 and Otud5

DIOPT Version :9

Sequence 1:	NP_648769.2	Gene:	CG7857 / 39671	FlyBaseID:	FBgn0026738	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_001277465.1	Gene:	Otud5 / 54644	MGIID:	1859615	Length:	567	Species:	Mus musculus

Alignment Length:	160	Identity:	40/160 - (25%)
Similarity:	71/160 - (44%)	Gaps:	23/160 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 PKLIELQQ---ITAKLSQRQLSLHNIPSDGDCLYQSIRHQLIVNALPGHSVQELREETANYVRAH 216
            |..:|.|:   ..|...::...:..:..||.||::::..| :......|.|  :|:...:|:..:
Mouse   193 PATVEQQEHWFEKALRDKKGFIIKQMKEDGACLFRAVADQ-VYGDQDMHEV--VRKHCMDYLMKN 254

  Fly   217 KDSLISYMIHPETGDILNDQQFEQYCHDIAKTHAWGGHIELKAISSLLRVPIEVIQAEGAP--TL 279
            .|...:|:          .:.|..|.:...|.:..|.|||::|::.:...|:||.|....|  |.
Mouse   255 ADYFSNYV----------TEDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQYSTEPINTF 309

  Fly   280 LGQEEFGGSPLIICYHRHIYQLGAHYNSTV 309
            .|..:....|:.:.|||:|     ||||.|
Mouse   310 HGIHQNEDEPIRVSYHRNI-----HYNSVV 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7857	NP_648769.2	COG5539	17..307	CDD:227826	37/156 (24%)
CG7857	NP_648769.2	OTU	178..305	CDD:280496	31/128 (24%)
Otud5	NP_001277465.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..117
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	145..175
		Cys-loop. /evidence=ECO:0000250	218..224		2/5 (40%)
		OTU	221..332	CDD:388712	33/128 (26%)
		Variable-loop. /evidence=ECO:0000250	273..283		2/9 (22%)
		His-loop. /evidence=ECO:0000250	324..329		4/9 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	413..499
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910