DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7857 and Nuf2

DIOPT Version :9

Sequence 1:	NP_648769.2	Gene:	CG7857 / 39671	FlyBaseID:	FBgn0026738	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_001012028.1	Gene:	Nuf2 / 304951	RGDID:	1307952	Length:	464	Species:	Rattus norvegicus

Alignment Length:	150	Identity:	33/150 - (22%)
Similarity:	63/150 - (42%)	Gaps:	14/150 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LQAKLQAMKKNAPKNNKNKRKEFLEEMARLEGELEQRHKAELKAAEAMEAPVLVEPVVKEPAEKP 98
            |:.:|...|.....:|:.|....|:|...|||:::. ..:|||..:..|     ..:::....|.
  Rat   291 LEVQLYQKKSQDLADNREKLSSILKESLNLEGQIDS-DSSELKKLKTEE-----NSLIRLMTLKK 349

  Fly    99 ETEVTDDDGIEEKEEQLAPNQRV-----SKAQKRRDKKAKEARAREAE---IKTELQNAANQPTP 155
            |...|....|.:|:|.:...:|.     :|.|::||...::..|...:   ||:.:|...:....
  Rat   350 ERLATMQFKINKKQEDVKQYKRTMIEDCNKVQEKRDAVCEQVTAINQDIHKIKSGIQQLRDAEKR 414

  Fly   156 KLIELQQITAKLSQRQLSLH 175
            :.::.|:|...|.......|
  Rat   415 EKLKSQEILVDLKSALEKYH 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7857	NP_648769.2	COG5539	17..307	CDD:227826	32/149 (21%)
CG7857	NP_648769.2	OTU	178..305	CDD:280496
Nuf2	NP_001012028.1	Interaction with the N-terminus of NDC80. /evidence=ECO:0000250	1..385		23/99 (23%)
		Nuf2	3..146	CDD:281753
		COG1340	175..443	CDD:224259	32/149 (21%)
		Interaction with the C-terminus of NDC80 and the SPBC24-SPBC25 subcomplex. /evidence=ECO:0000250	386..464		7/48 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000