DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7857 and Otud6a

DIOPT Version :9

Sequence 1:	NP_648769.2	Gene:	CG7857 / 39671	FlyBaseID:	FBgn0026738	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	XP_228584.1	Gene:	Otud6a / 302426	RGDID:	1560855	Length:	290	Species:	Rattus norvegicus

Alignment Length:	297	Identity:	103/297 - (34%)
Similarity:	165/297 - (55%)	Gaps:	29/297 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 EVSLEDIGARHRRERKDLQAKLQAMKKNAPKNNKNKRKEFLEEMARLEGELEQRHKAELKAAEAM 81
            |..|:.:..||.||:::|||.:|.:|.:.|||:|.:||:.|.::||||.|:||||:.||
  Rat     5 EHELQRVIRRHYREKRELQAHIQTLKASVPKNDKGRRKQLLSDIARLEAEMEQRHEQEL------ 63

  Fly    82 EAPVLVEPVVKEPAEKPETEVTDDDGIEEKE---EQLAPNQRVSKAQKRRDKKAKEARAREAEIK 143
                      ::..|.||:.| |....:.|:   |.:.|  |.:|:|||||::|...|.|:..:.
  Rat    64 ----------EKFGENPESGV-DSVTADLKKMNLENMPP--RPAKSQKRRDRRANLERRRQERMP 115

  Fly   144 TELQNAANQPTPKLIELQQITAKLSQRQLSLHNIPSDGDCLYQSIRHQLIVNALPGHSVQELREE 208
            .  ..|......:..|.:::.|.|..:.|.:..||:||.|:|::|:.||:.:.    :::.||..
  Rat   116 A--AQAEQLAAYRREEEEKVAAILGAKNLEMKTIPADGHCMYRAIQDQLVFSV----TIESLRYR 174

  Fly   209 TANYVRAHKDSLISYMIHPETGDILNDQQFEQYCHDIAKTHAWGGHIELKAISSLLRVPIEVIQA 273
            ||.|:|.|.|..:.:...||.|:....:.|.:||.||....:|||.:||:|:|.:|:.||||:||
  Rat   175 TAYYMRKHIDDFLPFFTEPEAGNFYTREDFLRYCDDIVHKASWGGQLELRALSHVLQTPIEVVQA 239

  Fly   274 EGAPTLLGQEEFGGSPLIICYHRHIYQLGAHYNSTVP 310
             .:|.::..||:...||.:.|..:....|.||||..|
  Rat   240 -NSPIIVIGEEYTRKPLTLVYLHYACDFGEHYNSVKP 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7857	NP_648769.2	COG5539	17..307	CDD:227826	100/292 (34%)
CG7857	NP_648769.2	OTU	178..305	CDD:280496	45/126 (36%)
Otud6a	XP_228584.1	COG5539	5..272	CDD:227826	100/292 (34%)
Otud6a	XP_228584.1	OTU	148..270	CDD:396767	45/126 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338864
Domainoid	1	1.000	121	1.000	Domainoid score	I5564
eggNOG	1	0.900	-	-		E1_COG5539
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	205	1.000	Inparanoid score	I3653
OMA	1	1.010	-	-		QHG54513
OrthoDB	1	1.010	-	-		D1541668at2759
OrthoFinder	1	1.000	-	-		FOG0003029
OrthoInspector	1	1.000	-	-		otm46141
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12419
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2018
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.870