DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7857 and Otud6b

DIOPT Version :9

Sequence 1:	NP_648769.2	Gene:	CG7857 / 39671	FlyBaseID:	FBgn0026738	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	XP_038965351.1	Gene:	Otud6b / 297911	RGDID:	1310024	Length:	333	Species:	Rattus norvegicus

Alignment Length:	323	Identity:	122/323 - (37%)
Similarity:	188/323 - (58%)	Gaps:	57/323 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GDVAIAE--LESRLDEVSLEDIGARHRRERKDLQAKLQAMKKNAPKNNKNKRKEFLEEMARLEGE 66
            |.:.:.|  |...||:.  |.:..|||:|:|:||||:|.||...|||:|.:||:..|::|:||.|
  Rat    27 GHLVVMEEILAEELDDE--EQLMRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLERE 89

  Fly    67 LEQRHKAELKAAEAMEAPVLVEPVVKEPAEKPETEVTDDDGIEEKEEQLAPN----------QRV 121
            :||:|:.||:                      :.::|..|   .|.:.:|.|          .|:
  Rat    90 MEQKHREELE----------------------QLKLTFKD---SKIDSVAVNVSNLVLDSQPPRI 129

  Fly   122 SKAQKRRDKKA-----KEARAREAEIKTELQNAANQPTPKLIELQQITAKLSQRQLSLHNIPSDG 181
            |||||||:|||     :|.|..||||: .|..|.:..:.||.::      |:.|:|.:.:|||||
  Rat   130 SKAQKRREKKAALEKEREERIAEAEIE-NLSGARHLESEKLAQI------LAARELEIKHIPSDG 187

  Fly   182 DCLYQSIRHQLIV--NALPGHSVQELREETANYVRAHKDSLISYMIHPETGDILNDQQFEQYCHD 244
            .|:|.::..||..  :||   :|..||.:||.|:::|.|..:.::.:|.|||:...::|.:||.|
  Rat   188 HCMYGALEDQLREQDSAL---TVATLRRQTAEYMQSHSDDFLPFLTNPNTGDMYTPEEFGKYCDD 249

  Fly   245 IAKTHAWGGHIELKAISSLLRVPIEVIQAEGAPTLLGQEEFGGSPLIICYHRHIYQLGAHYNS 307
            |..|.||||.:||:|:|.:|:.|||::||:..|.::| ||:..:||::.|.||.|.||.||||
  Rat   250 IVNTAAWGGQLELRALSHILKTPIEILQADAPPIIVG-EEYPRNPLVLVYMRHAYGLGEHYNS 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7857	NP_648769.2	COG5539	17..307	CDD:227826	115/306 (38%)
CG7857	NP_648769.2	OTU	178..305	CDD:280496	54/128 (42%)
Otud6b	XP_038965351.1	COG5539	43..311	CDD:227826	115/305 (38%)
Otud6b	XP_038965351.1	OTU	184..309	CDD:396767	54/128 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I5564
eggNOG	1	0.900	-	-		E1_COG5539
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6064
Inparanoid	1	1.050	205	1.000	Inparanoid score	I3653
OMA	1	1.010	-	-		QHG54513
OrthoDB	1	1.010	-	-		D1541668at2759
OrthoFinder	1	1.000	-	-		FOG0003029
OrthoInspector	1	1.000	-	-		otm46141
orthoMCL	1	0.900	-	-		OOG6_102788
Panther	1	1.100	-	-	LDO	PTHR12419
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2018
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840