DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7857 and otub-3

DIOPT Version :9

Sequence 1:	NP_648769.2	Gene:	CG7857 / 39671	FlyBaseID:	FBgn0026738	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_001255319.1	Gene:	otub-3 / 177679	WormBaseID:	WBGene00009007	Length:	330	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	95/301 - (31%)
Similarity:	141/301 - (46%)	Gaps:	36/301 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KDLQAKLQAMKKNAPKNNKNKRKEFLEEMARLEGELEQRHKAELKAAEAMEAPVLVEPVVKEPAE 96
            |.|..|:.|.||.|...||..:||...|..::|.|:::|||.||:.|:..|....|      |||
Worm    43 KQLPGKILAKKKAAKCGNKQMQKEAGAECEKMEKEMDERHKKELEEAKKPEESEAV------PAE 101

  Fly    97 KPET----------EVTDDDGIEEKEEQLAPNQRVS-KAQKRRDKKAKEARAREAEIKTELQNAA 150
            .||.          |.:|:||............::| ||.|::|||.|.|...:|....:.:...
Worm   102 NPEASTLSPPSPNPEGSDNDGEGPSSSAFYKTVKISNKAAKKQDKKKKTADKMKAAEAADKEAGK 166

  Fly   151 NQPTPKLIELQQITAKLSQRQLSLHNIPSDGDCLYQSIRHQLIVNALPGHSVQELREETANYVRA 215
            ||.:.:.:|...:...|::..:.:.:||:||||:|.:|.|||....:. .||::||:....|:|.
Worm   167 NQLSDRQMEKAAVKEMLAEDHMKMIDIPADGDCMYNAISHQLQEEGIE-ISVRKLRKRCGTYMRE 230

  Fly   216 HKDSLISYMIHPETGDILN---DQQFEQYCHDIAKT----HAWGGHIELKAISSLLRVPIEVIQA 273
            |.:.     ..|...|:.|   |..:..|...:...    ..|||.:||||.|.:....|.|.:.
Worm   231 HSED-----FRPFIEDMANMDSDSSWATYLGGVENVAEIGGVWGGELELKACSMIFEKTIVVYKQ 290

  Fly   274 EGAPTLLGQEEFGGSP----LIICYHRHIYQLGAHYNSTVP 310
            .|....:|:|.  .||    |.:.:.||.|.||.|||||.|
Worm   291 YGGRHTIGEEY--SSPKDRALRVVFLRHAYSLGEHYNSTCP 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7857	NP_648769.2	COG5539	17..307	CDD:227826	91/296 (31%)
CG7857	NP_648769.2	OTU	178..305	CDD:280496	43/137 (31%)
otub-3	NP_001255319.1	OTU	194..324	CDD:334900	43/137 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165190
Domainoid	1	1.000	65	1.000	Domainoid score	I6670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6064
Inparanoid	1	1.050	128	1.000	Inparanoid score	I3249
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54513
OrthoDB	1	1.010	-	-		D1541668at2759
OrthoFinder	1	1.000	-	-		FOG0003029
OrthoInspector	1	1.000	-	-		oto19737
orthoMCL	1	0.900	-	-		OOG6_102788
Panther	1	1.100	-	-	LDO	PTHR12419
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3778
SonicParanoid	1	1.000	-	-		X2018
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940