DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cocoon and HRP1

DIOPT Version :9

Sequence 1:	NP_001261874.1	Gene:	cocoon / 39665	FlyBaseID:	FBgn0036496	Length:	318	Species:	Drosophila melanogaster
Sequence 2:	NP_014518.1	Gene:	HRP1 / 853997	SGDID:	S000005483	Length:	534	Species:	Saccharomyces cerevisiae

Alignment Length:	315	Identity:	88/315 - (27%)
Similarity:	142/315 - (45%)	Gaps:	35/315 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 AEEDGTLLLSTLQAQFPESSGLQYRNVDTKAVRGVRSNEGRLYSPSEETG--WGEYHYFCVFPKK 81
            :::|||       |...|.|....:| :.|......:|.....|.:..:|  |.:........::
Yeast    75 SKQDGT-------ANDKEGSNEDTKN-EKKQESATSANANANASSAGPSGLPWEQLQQTMSQFQQ 131

  Fly    82 NKRQSEDNLENSTAKTKRTEAHL---RCFDLIVLGLSYNTTEQDLREYFETYGDVVKAEIKKDTR 143
            ...||....:.:..|.:|::|.|   .| .:.:.||:::|||.:|||||..||.|...:|.||..
Yeast   132 PSSQSPPQQQVTQTKEERSKADLSKESC-KMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPA 195

  Fly   144 SGHSKGFGFVRFGSYDVQMHVLSKRHSIDGRWCEVK--VPASRGMGNQEPGKVFVGRCTEDIEAD 206
            :|.|:||||:.|........|:..:|.:||:..:.|  :|...   ..:.||:|||....|:...
Yeast   196 TGRSRGFGFLSFEKPSSVDEVVKTQHILDGKVIDPKRAIPRDE---QDKTGKIFVGGIGPDVRPK 257

  Fly   207 DLREYFSKFGEVID--VFIPK---PFRAFSFVTFLDPYVPRVVCGEKHI-IKGVSVHVSTADKKN 265
            :..|:||::|.:||  :.:.|   ..|.|.|||:........||..|.| .|...:.:..|:.::
Yeast   258 EFEEFFSQWGTIIDAQLMLDKDTGQSRGFGFVTYDSADAVDRVCQNKFIDFKDRKIEIKRAEPRH 322

  Fly   266 VQNKNQLFQTNNYNNLDNNFKMQPANNFRMHPANNFSMHSFNP--HGYQMNRVMN 318
            :|.|:   ..|..||..||...:..|   .....:|:....||  .||  |.:||
Yeast   323 MQQKS---SNNGGNNGGNNMNRRGGN---FGNQGDFNQMYQNPMMGGY--NPMMN 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cocoon	NP_001261874.1	RRM1_TDP43	108..184	CDD:240767	29/77 (38%)
cocoon	NP_001261874.1	RRM2_TDP43	193..262	CDD:240768	22/74 (30%)
HRP1	NP_014518.1	PABP-1234	<144..463	CDD:130689	74/238 (31%)
		RRM1_Hrp1p	161..236	CDD:409991	28/74 (38%)
		RRM2_Hrp1p	244..321	CDD:409767	23/76 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910