Protein Alignment cocoon and NSR1

DIOPT Version :10

• Sequence 1: NP_648764.1
• Gene: cocoon / 39665
• FlyBaseID: FBgn0036496
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_011675.1
• Gene: NSR1 / 853064
• SGDID: S000003391
• Length: 414
• Species: Saccharomyces cerevisiae
• Alignment Length: 256
• Identity: 66/256 - (25%)
• Similarity: 105/256 - (41%)
• Gaps: 60/256 - (23%)

  Fly     7 SEKEGDEPIELPAEEDGTLLLSTLQAQFPESSGLQYRNVDTKAVRGVRSNEGRLYSPSEETGWGE 71
            |:...||..|...||       |.:.:..|||     :.|:.:     |:.....|..||:
Yeast    93 SDSSSDEEEEEEKEE-------TKKEESKESS-----SSDSSS-----SSSSDSESEKEES---- 136

  Fly    72 YHYFCVFPKKNKRQSEDNLE-------NSTAKTKRTEAHLRCFDLIVLGLSYNTTEQDLREYFET 129
                    ...||:|||..|       |...|.:.||.....|   |..||::..::.|::.||.
Yeast   137 --------NDKKRKSEDAEEEEDEESSNKKQKNEETEEPATIF---VGRLSWSIDDEWLKKEFEH 190

  Fly   130 YGDVVKAEIKKDTRSGHSKGFGFVRF--GSYDVQMHVLSKRHSIDGRWCEVKVPASRGMGNQEPG 192
            .|.|:.|.:..:..:..|:|:|:|.|  .||..:.....:...||||.....:..|:..||.:..
Yeast   191 IGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSKPAGNNDRA 255

  Fly   193 K------------VFVGRCTEDIEADDLREYFSKFGEVIDVFIP------KPFRAFSFVTF 235
            |            :|:|..:.:.:.|.:.|.|:|.|||:.|.||      :| :.|.:|.|
Yeast   256 KKFGDTPSEPSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQP-KGFGYVQF 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cocoon	NP_648764.1	TDP43_N	3..78	CDD:465833	15/70 (21%)
		RRM1_TDP43	108..181	CDD:409760	20/74 (27%)
		RRM2_TDP43	193..262	CDD:409761	17/61 (28%)
NSR1	NP_011675.1	RRM1_gar2	169..244	CDD:409881	21/77 (27%)
		RRM2_gar2	269..341	CDD:409882	16/48 (33%)