Protein Alignment cocoon and NGR1

DIOPT Version :10

• Sequence 1: NP_648764.1
• Gene: cocoon / 39665
• FlyBaseID: FBgn0036496
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_009771.3
• Gene: NGR1 / 852513
• SGDID: S000000416
• Length: 672
• Species: Saccharomyces cerevisiae
• Alignment Length: 353
• Identity: 66/353 - (18%)
• Similarity: 98/353 - (27%)
• Gaps: 167/353 - (47%)

  Fly   107 FDLIVLGLSYNTTEQDLREYFET-YGDVVKAEIKKDTRSGHSKGFGFVRFGSYDVQMHVLSKRHS 170
            |.|.|..||...||.||...|:| :..|....:..|..:|.|:.|||||||..|.:...|.:
Yeast   192 FSLFVGDLSPTATEADLLSLFQTRFKSVKTVRVMTDPLTGSSRCFGFVRFGDEDERRRALIE--- 253

  Fly   171 IDGRWCEVKV------------------------------------------------------- 180
            :.|:|.:.:.
Yeast   254 MSGKWFQGRALRVAYATPRNNMMLQLQEQQQQQQQLQQQHQQLDQEDNNGPLLIKTANNLIQNNS 318

  Fly   181 ------------PASRGMG----------------NQEPGK--VFVGRCTEDIEADDLREYFSKF 215
                        |.....|                |.:|..  ||||..........||..|..|
Yeast   319 NMLPLNALHNAPPMHLNEGGISNMRVNDSLPSNTYNTDPTNTTVFVGGLVPKTTEFQLRSLFKPF 383

  Fly   216 GEVIDVFIPKPFRAFSFVTFLDPYVPRVVCGEKHI------------------------------ 250
            |.:::|.||.. :...||.|           ||.|
Yeast   384 GPILNVRIPNG-KNCGFVKF-----------EKRIDAEASIQGLQGFIVGGSPIRLSWGRPSSSN 436

  Fly   251 ------IKGVSVHVST------------ADKKNV-----QNKNQLF-----QTNNYNNLDNNFKM 287
                  |.|.|.::|:            .:.|.:     ::|.:||     |.......|.||.|
Yeast   437 AKTNSTIMGASQYMSSNGLRAPSAASSVDNSKQILEQYAEDKRRLFLHQQQQQQQQQQQDGNFSM 501

  Fly   288 QPANNFRMHPANNFSMHSFNPHGYQMNR 315
            :...:      ||:  :::|.:.|..|:
Yeast   502 EQMAH------NNY--YNYNNYDYHRNK 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cocoon	NP_648764.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	25/140 (18%)
		RRM2_TDP43	193..262	CDD:409761	22/118 (19%)
NGR1	NP_009771.3	RRM1_NGR1_NAM8_like	35..180	CDD:410023
		RRM2_NGR1_NAM8_like	191..270	CDD:410025	26/80 (33%)
		RRM3_NGR1_NAM8_like	359..430	CDD:409782	18/82 (22%)